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Green synthesis of Titanium Dioxide nanoparticles from Capsicum annum extract and its Characterization and Evaluation of antioxidant activity

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Author Affiliations

  • 1Department of Biotechnology, Nrupathunga University, Bengaluru, Karnataka, India
  • 2Department of Biotechnology, Nrupathunga University, Bengaluru, Karnataka, India
  • 3Department of Biotechnology, Nrupathunga University, Bengaluru, Karnataka, India
  • 4Department of Biotechnology, Nrupathunga University, Bengaluru, Karnataka, India
  • 5Insearch Laboratory, Bengaluru, Karnataka, India

Res. J. Recent Sci., Volume 15, Issue (3), Pages 36-41, July,2 (2026)

Abstract

The green synthesis approach for producing nanoparticles has significantly increased due to their adaptable and flexible nature. Titanium dioxide nanoparticles (TiO₂ NPs) were synthesised using Capsicum annuum extract through an eco-friendly green synthesis approach. Plant-derived phytochemicals acted as natural reducing and stabilising agents, enhancing nanoparticle bioactivity. The antioxidant potential of the synthesized TiO₂ nanoparticles was evaluated using DPPH, Ferrozine, and FRAP assays. The nanoparticles exhibited significant free-radical scavenging activity with a clear dose-dependent response, strong ferric-reducing capacity, and surface accessible ferrous ion reactivity, indicating functional antioxidant behaviour. Structural and chemical characterisation using UV–Visible spectroscopy and FTIR spectroscopy confirmed formation of nanoparticles and phytochemical functionalization. The results demonstrate that Capsicum annuum-mediated TiO₂ nanoparticles are structurally stable, functionally active, and biologically relevant, highlighting their potential for biomedical and pharmaceutical applications involving oxidative stress modulation.

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