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Sustainable synthesis and Physicochemical study of fused Pyrimidones by using Natural catalyst

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Author Affiliations

  • 1Chemistry Department, Royal College of Arts, Science and Commerce (Autonomous), Mira Road (East), Dist. Thane 401107, Maharashtra, India
  • 2Chemistry Department, Royal College of Arts, Science and Commerce (Autonomous), Mira Road (East), Dist. Thane 401107, Maharashtra, India

Res.J.chem.sci., Volume 16, Issue (2), Pages 53-56, June,18 (2026)

Abstract

Pyrimidone derivatives have been synthesized by grinding 1,3-Diketone heterocycle, Aromatic Aldehyde and Urea/Thiourea with catalytic amount of Fresh limejuice as a natural catalyst. The comparative physiochemical studies were done with respect to the reaction conversion, purity, atom economy, simplicity of reaction and easy work-up of the multicomponent reaction. The actual structures of all the products confirmed by different chemical test along with Chromatographic analysis, melting point and spectral technique like IR, 1H NMR and 13C NMR.

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