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Synthesis and Characterization of caffeine Complexes [M (caf) 4X2] M = Ni(II), Cu(II), Zn(II), Cd(II) X = SCN-, CN-; caf : caffeine

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Author Affiliations

  • 1 Equipe Métallation, complexes moléculaires et applications, Université Moulay Ismail, faculté des sciences, Meknès, BP 11201 Zitoune, 50000 MOROCCO

Res.J.chem.sci., Volume 4, Issue (2), Pages 42-48, February,18 (2014)

Abstract

A series of complexes [M(caf)4X2] where X = cyano,thiocyanato , caf=caffeine ,and M = Ni (II), Cu (II), Zn (II) and Cd (II) were prepared. The prepared complexes were characterized by elemental analysis, conductance measurement, UV-Visible and FT-IR spectral analysis. The conductivity measurements reveal that the complexes are nonelectrolyte. The elemental analysis showed the formation of 1,4,2 (metal, caffeine, cyano or thiocyanato) complexes. The infrared and UV-visible data indicating a monodentate coordination of the four caffeine by N9 nitrogen atom and two cyano or thiocyanato in trans and cis octahedral geometry.

References

  1. Joshi Ajit, Pathak Abhishek and Kumar Asheesh, Illicit Drugs and their Assessment: A Brief Review, Research Journal of Forensic Sciences, 1(1), 8-14 (2012)
  2. Naina Thangaraj, Siddharth Sharan and Vuppu Suneetha, Role of Proteus mirabilis in Caffeine Degradation – A Preliminary Bioinformatics Study, Research Journal of Recent Sciences,2(ISC-2012), 33-40 (2012)
  3. Kaur Satindar, Chattopadhyay D.P. and Varinder Kaur,Research Journal of Engineering Sciences,1(4), 21-26 (2012)
  4. Tragonos F., Kapuscinski J. and Darzynkiewicz Z., Caffeine modulates the effects of DNA-intercalating drugs in vitro: A flow cytometric and spectrophotometric analysis of caffeine interaction with novantrone, doxorubicin, ellipticine, and the doxorubicin analogue AD198, Cancer Res., 51(3), 682–3689 (1991)
  5. Davies DB. Veselkov DA. Djimant LN. Veselkov AN., Hetero-association of caffeine and aromatic drugs and their competitive binding with a DNA oligomer., Eur Biophys J. 30, 354–366 (2001)
  6. David L. Cozar O. Forizs E. Craciun C., Ristoiu D. and Balan C., Local structure analysis of some Cu(II) theophylline complexes, Spectrochimica Acta Part A, 55, 2559–2564 (1999)
  7. Saedia M. Al-Hashimi, Mohean E.Al-Jaboori. Shayma A.S. Al-Azawi.,Synthesis and studies of Mixed- ligand complexes of Some Transition Elements, Um-Salama Science Journal (2006)
  8. Kettle S.F.A., Coordination compounds, Thomas Nelson and Sons, London, 165(1975)
  9. Ucun F., Saglam A. and Guclu V. Molecular strutures and vibrational frequencies of Xanthine and its methyl derivatives (caffeine and theobromine)by ab initio hatree-fock and density functional theory calculations., j.spectrochimica ACTA PARTA 67, 342-349 (2007)
  10. H.G.M.Edwards, D.W. Faewell, L.F.C. de Oliveira, j.-M. Alia, M. le Hyaric, M.V. de Ameida, Anal.chimi. Acta 532, 177 (2005)
  11. Elizabeth H. Griffith & Elmer L. Amma. Reaction of PtCl2– with theophylline: X-ray crystal structures of bis(theophyllinium) tetrachloroplatinate(II) and theophyllinium trichlorotheophyllineplatinate(II)., J.C.S. Chem. Commun., 322-324 (1979)
  12. Rajasekar K. Ramachandramoorthy T. Paulraj A., Microwave Assisted Synthesis, Structural Characterization and Biological Activities of 4-Aminoantipyrine and Thiocyanate Mixed Ligand Complexes, Research Journal of Pharmaceutical Sciences, 1(4), 22-27 (2012)
  13. Michael Bron. Rudolf Holze., Cyanate and thiocyanate adsorption at copper and gold electrodes as probed by in situ infrared and surface-enhanced raman spectroscopy, Journal of Electroanalytical Chemistry, 385(1), 105-113(1995)
  14. Satwinder S., Marwaha Jasjest Kaur, Gurvinder S. Sodhi, Structure determination and anti-inflammatory activity of some purine complexes, Met Based Drugs, 2(1), 13–17 (1995)
  15. Shaker A., Yang Farina. Sadia Mahmmo. Mohean Eskender., Synthesis and Characterization of Mixed Ligand Complexes of Caffeine, Adenine and Thiocyanate with Some Transition Metal Ions, Sains Malaysiana., 39(6), 957–962 (2010)
  16. Beck H.T. "10 Caffeine, Alcohol, and Sweeteners". In Ghillean Prance; Mark Nesbitt. Cultural History of Plants. New York: Routledge., 179, (2004)
  17. R. Matissek, . European “Evaluation of xanthine derivatives in chocolate nutritional and chemical aspects,” Zeitschrift fur Lebensmittel -Untersuchung und –Forschung.,205(3), 175– 184 (1997)
  18. Satwinder. S. Marwaha. Jasjest Kaur. Gurvinder S. Sodhi,. Structure determination and anti- inflammatory activity of some purine complexes., Met Based Drugs., 2(1), 13–17(1995)
  19. Katsuyuki Aok. Hiroshi Yamazaki., Interactions of tetrakis(-µ-carboxylato)dirhodium(II), an antitumour agent, with nucleic acid bases. X-Ray crystal structures of [Rh2(acetato)4(theophylline)2] and [Rh2(acetato) 4 (caffeine)2]., J. Chem. Soc. Chem. Commun., 186-188 (1980)
  20. Milan Melnik. Binuclear. Binuclear., caffeine adducts of Cu(II) acetate and Cu(II) chloracetates with unusually high antiferromagnetic interaction, J. inorg. Nucl. Chem., 43, 3035-3038 (1981)