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Synthesis of Newly Thiocarbamides using Substituted Isothiocyanates

Author Affiliations

  • 1H.V.P.M.ís College of Engineering and Technology, Amravati-444605, MS, INDIA

Res.J.chem.sci., Volume 3, Issue (1), Pages 92-93, January,18 (2013)


A series of 1,3-bis (2- substitutedamino-6-substituted-imino-1,3,5-thiadiazin- 4- yl)-thiocarbamides [3a(i) to 3f (iii)] havebeen obtained by basification of their hydrochlorides [2a(i) to 2f (iii)].The latter were synthesized by the interaction of 1,3-bis (N-substitutedamidinothiocarbamido)- thiourea (1) and N-aryl/alkylisocyanodichlorides in 1:2 molar ratio. Thecompound (1) was prepared initially by the condensation of aryl/alkylisothiocyanate and 1, 3-diformamidinothiourea in 1:2molar ratios. The structure of all these compounds was established on the basis of IR and NMR spectral data.


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