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Assessment of Onchocerciasis and Ivermectin Treatment in UDI and IGBO-ETITI Local Government Areas of Enugu State, Nigeria

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Author Affiliations

  • 1 Federal University of Technology, Owerri, Imo State, NIGERIA
  • 2University of Nigeria, Nsukka, Awka, Anambra State, NIGERIA
  • 3Nnamdi Azikiwe University, Awka, Anambra State, NIGERIA

Int. Res. J. Medical Sci., Volume 1, Issue (5), Pages 19-21, June,28 (2013)

Abstract

Assessment of onchocerciasis and the efficacy of Ivermectin chemotherapy were carried out in Udi and Igbo-Etiti Local Government Areas of Enugu State using Rapid Assessment Method (RAM) and skin biospsies for onchocercal microfilaria. Out of the 1362 subjects examined and dosed with Ivermectin at a standard dosage of 150 mg/15 kg body weight, 1158 (85%) were infected with onchocerciasis. Infection was independent of sex (P0.05), but dependent on age and location of the communities in relation to water bodies (r=100, P 0.05). Post-drug survey was carried out in the communities to monitor the effect of Ivermectin chemotherapy in the treated communities by using RAM and re-skin snipping of the subjects. Results obtained showed that there are significant reductions in the disease prevalence when compared to the pre-drug onchocercal prevalence (P 0.05). Efficacy was also found to be dependent on age and sex of the subjects.

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