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Antihyperlipidemic activity of fresh juice of Benincasa hispida cogn.

Author Affiliations

  • 1Periyar College of Pharmaceutical Sciences, Tiruchirappalli-21, Tamilnadu, India
  • 2Periyar College of Pharmaceutical Sciences, Tiruchirappalli-21, Tamilnadu, India
  • 3Periyar College of Pharmaceutical Sciences, Tiruchirappalli-21, Tamilnadu, India
  • 4Periyar College of Pharmaceutical Sciences, Tiruchirappalli-21, Tamilnadu, India

Res. J. of Pharmaceutical Sci., Volume 8, Issue (2), Pages 18-20, December,30 (2019)


India has a long history of traditional knowledge on dietary sources with medicinal properties that draws attention of the current investigation of Benincasa hispida, May not produces side effects while treating the hypercholesteremia and obesity. Evaluation of anti hyperlipidemic activity by using triton-x 100 along with atherogenic diet induced obesity and anorectic activity in animal models by fresh juice of Benincasa hispida dose 0.9ml/200g were Oral administration produces a significantly reduces the serum lipid parameters such as Cholesterol, Triglycerides, Low Density Lipoprotein (LDL), Very Low Density Lipoprotein (VLDL) and increased in High Density Lipoprotein (HDL) in rats as compared to control statistically. Our results shows that Benincasa hispida possess anti hyperlipidemic activity with no toxicity and better therapeutic of the treatment of anti-hyperlipidemia and anti obesity.


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