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Investigation of Herbal Extract as Hepatoprotective

Author Affiliations

  • 1L.M. College of Science and Technology, Pharmacy Wing, Jodhpur, Rajasthan, INDIA
  • 2 Department of Pharmaceutics, Indian Institute of Technology, Banaras Hindu University, Varanasi, UP, INDIA

Res. J. of Pharmaceutical Sci., Volume 1, Issue (3), Pages 16-18, November,30 (2012)

Abstract

In this paper we investigate hepatoprotective activity of herbal extracts of amorphophallus campanulatus, casuarina equistfolia, orthosiphon stamineus, pterocarpus santalinus, aegle marmelos, chamomile recutita ptero corpus marsupial, luffa echinata and Embelia Ribes. Results of the studies showed that all tested extract have moderate to excellent hepatoprotective activity with marmelos species showing the maximum. Further optimization of the study will results in potent herbal compounds as hepatoprotectives.

References

  1. Jain S. and Dixit V.K. et al., Antioxident and heapotoprotective activity of ethenolic and aqueous extract of Amorphophalluscompanulatus Roxb. Tuber, Acta, poloniac pharmaceutica – Drug research, 66(4),423-428 (2009)
  2. Ahsan R.M. and Islam M. et al, Hepatoprotective activity of methanol extract of same of medicinal plants against CCl-included hepatotoxicity in Rat, European Journal of scientific Research 37(2), 302-310 (2009)
  3. Maheshwari C. and Maryanimal R. et al Hepatoprotective activity orthosiphon stamineus on liver damage caused by paracetamol in Rat, Jordan Journal of Biological science,1(3), 105-108 (1995)
  4. T.S. Mohammad Saleem and C. Madhusudan Chetty, Hepatoprotective herbs – A Review, Int. J. Pharma. Sci.,1(1), 1-5 (2005)
  5. Ajay Kumar Gupta, Neelam Mishra, Hepatoprotective activity of aqueous ethanolic extract of chemomile capitula in paracetamol intoxicated Albino Rats, American Journal of Pharmacology and toxicology,1(1),17-20 (2006)
  6. Mankani K.L. and Krishna V., et. Al Evaluation of hepatoprotective activity of stem bark of pterocarpus marsupium Roxb, Indian J. Pharmcol June,37(3), 165-168 (2005)
  7. Manjunath B.K., Hepatoprotective activity of ptero carpus santalinus L.F., Indian Journal of pharmacology,38(1), 25-28 (2006)
  8. Nohid Tabassum and Shyam S. Agrawal, Hepatatoprotective activity of emblica Ribes against paracetamol induced acute hepotocellular damage in mice, J.K. practitioner,10(1), 43-44 (2003)
  9. Bahar Ahmad Tanveer alam and Shah A. Khan, Hepatatoprotective activity of luffa echinata fruits, Journal of Ethanopharmacology, 7687-89 (2001)
  10. Agarwal S.S., Development of the Hepatatoprotective formulation from plant sources, In:Pharmocology and the rapeutics in the New Millennium, Edited by Gupta SK, Narosa Publishing House, New Delhi, 357-358 (2001)
  11. Handa SS, Sharma A, Chakraborti KK, Natural products and plants as liver protecting drugs, Fitoterapia,57(5),307-352 (1986)
  12. Karandikar S.M., Joglekar G.V., Chitale G.K. and Balwani J.H., Protection by indigenous drugs against hepatotoxic effect of carbon tetrachloride, a long term study, Acta Pharmacologia et Toxicologia (Copenhagen), 20, 274 (1963)
  13. Radha K.D. and Yogesh K.C., Herbal medicines for liver diseases, Digestive Diseases and Science,50(10),1807-1812 (2005)
  14. Stickel F. and Schuppan D., Herbal medicine in the treatment of liver diseases, Digestive and liver Disease,39, 293-304 (2007)
  15. Thyagarajan S.P., Jayaram S., Gopalkrishna V., Hri R. Jeyakumar P. and Sripathi M.S., Herbal medicines for liver diseases in India, J Gastroenterol Hepatol, 17(3),370-6 (2002)