@Research Paper
<#LINE#>Comparison of the osteopontin gene expression in gingival tissue related to chronic and acute periodontitis mRNA expression of osteopontin in gingival tissue of the chronic and acute periodontitis<#LINE#>M.@Satary , Babadi V.@Yousefi,A.@Mohammadbeygi ,F.@Yeganeh ,B.@Kosary <#LINE#>1-5<#LINE#>1.ISCA-RJRS-2018-035.pdf<#LINE#>Department of Immunology, Shahidbeheshti University, Tehran, Iran@Department of Biology, Payamenoor University, Tehran, Iran@Department of Immunology, Shahidbeheshti University, Tehran, Iran@Department of Immunology, Shahidbeheshti University, Tehran, Iran and Department of Biology, Payamenoor University, Tehran, Iran@Department of Immunology, Shahidbeheshti University, Tehran, Iran<#LINE#>28/4/2018<#LINE#>6/9/2018<#LINE#>Bacterial infection of periodontal tissue refers to periodontal disease which can lead to bone resorption and tooth loss in severe cases. During the disease procedure, both innate and adaptive immune responses involve that trigger inflammation. Osteopontin (OPN) is an extracellular glycosylated phosphoprotein which increases in inflammation status such as periodontitis. Correlation of the OPN expression and severity of periodontal tissue infection does not investigated yet. Therefore this study assessed OPN expression level in chronic and acute periodontitis to introducing a new correlation between them. For this purpose, gingival tissue samples were collected from 20 patients with chronic periodontitis and 10 persons without obvious sign of periodontitis. Total RNA related to each tissue sample was extracted after homogenizing. The expression of OPNgen (amount of corresponding mRAN) was evaluated by real-time PCR method. Expression of the OPNgene decreased in both types of examined periodontitis and reduced more significantly in acute cases (P<0.05). Statistical analysis revealed presence of significant correlation between negative fold change of gene expression and severity of infectious in periodontal tissue (P<0.05). Results suggest OPN has a possible important role in protection against periodontopathic bacteria and bone lesion, but disease progression accompanied by reduced expression may be due toOPN producer cell death.<#LINE#>Lerner U.H. (2004).@New molecules in the tumor necrosis factor ligand and receptor superfamilies with importance for physiological and pathological bone resorption.@Critical Reviews in Oral Biology & Medicine, 15(2), 64-81.@Yes$Page R.C. and Kornman K.S. (1997).@The pathogenesis of human periodontitis: an introduction.@Periodontology 2000, 14(1), 9-11.@Yes$Cochran D.L. (2008).@Inflammation and bone loss in periodontal disease.@Journal of periodontology, 79(8S), 1569-1576.@Yes$Ohlrich E.J., Cullinan M.P. and Seymour G.J. (2009).@The immunopathogenesis of periodontal disease.@Australian dental journal, 54, S2-S10.@Yes$Demmer R.T. and Papapanou P.N. (2010).@Epidemiologic patterns of chronic and aggressive periodontitis.@Periodontology 2000, 53(1), 28-44.@Yes$Tanabe N., Wheal B.D., Kwon J., Chen H.H., Shugg R.P., Sims S.M., Goldberg H.A. and Dixon S.J. (2011).@Osteopontin Signals through Calcium and Nuclear Factor of Activated T Cells (NFAT) in Osteoclasts A novel RGD-Dependent Pathway Promoting Cell Survival.@Journal of Biological Chemistry, 286(46), 39871-39881.@Yes$Chang I.C., Chiang T.I., Yeh K.T., Lee H. and Cheng Y.W. (2010).@Increased serum osteopontin is a risk factor for osteoporosis in menopausal women.@Osteoporosis international, 21(8), 1401-1409.@Yes$Standal T., Borset M. and Sundan A. (2004).@Role of osteopontin in adhesion, migration, cell survival and bone remodeling.@Exp Oncol, 26(3), 179-184.@Yes$Ahn H., Kim J.M., Lee K., Kim H. and Jeong D. (2012).@Extracellular acidosis accelerates bone resorption by enhancing osteoclast survival, adhesion, and migration.@Biochemical and biophysical research communications, 418(1), 144-148.@Yes$Huang W., Carlsen B., Rudkin G., Berry M., Ishida K., Yamaguchi D.T. and Miller T.A. (2004).@Osteopontin is a negative regulator of proliferation and differentiation in MC3T3-E1 pre-osteoblastic cells.@Bone, 34(5), 799-808.@Yes$Yumoto K., Ishijima M., Rittling S.R., Tsuji K.T., Suchiya Y., Kon S., Nifuji A., Uede T., Denhardt D.T. and Noda M. (2002).@Osteopontin deficiency protects joints against destruction in anti-type II collagen antibody-induced arthritis in mice.@Proc. Natl. Acad. Sci. U.S.A., 99(7), 4556-4561.@Yes$Rajkarnikar J., Thomas B.S. and Rao S.K. (2013).@Inter-relationship between rheumatoid arthritis and periodontitis.@Kathmandu Univ Med J (KUMJ), 11(41), 22-26.@Yes$Ogrendik M. (2013).@Rheumatoid arthritis is an autoimmune disease caused by periodontal pathogens.@International journal of general medicine, 6, 383-386.@Yes$Kido J.I., Nakamura T., Asahara Y., Sawa T., Kohri K. and Nagata T. (2001).@Osteopontin in gingival crevicular fluid.@Journal of periodontal research, 36(5), 328-333.@Yes$Wiebe C.B. and Putnins E.E. (2000).@The periodontal disease classification system of the American Academy of Periodontology-an update.@Journal-canadian dental association, 66(11), 594-597.@Yes$Andrew J. Holloway, Dileepa S. Diyagama, Ken Opeskin, Jenette Creaney, Bruce W.S. Robinson, Richard A. Lake and David D.L. (2006).@A Molecular Diagnostic Test for Distinguishing Lung Adenocarcinoma from Malignant Mesothelioma using Cells Collected from Pleural Effusions.@Bowtell Clin Cancer Res., 12(17).@Yes$UCSC Genome Browser (2017). University of California Santa Cruz, Genomics Institute, http://genome. ucsc.edu/@undefined@undefined@Yes$Sharma C.D. and Pradeep A.R. (2006).@Gingival crevicular fluid osteopontin levels in periodontal health and disease.@Journal of period ontology, 77(10), 1674-1680.@Yes$Hans S. and Mali A.M. (2012).@Estimation and comparison of osteopontin levels in plasma in subjects with healthy periodontium and generalized chronic periodontitis and its assessment after scaling and root planing.@J Indian Soc Periodontol, 16(3), 354-357.@Yes$Walker C.G., Dangaria S., Ito Y., Luan X. and Diekwisch T.G. (2010).@Osteopontin is required for unloading-induced osteoclast recruitment and modulation of RANKL expression during tooth drift-associated bone remodeling, but not for super-eruption.@Bone, 47(6), 1020-1029.@Yes
<#LINE#>Assessment of knowledge on poly cystic ovarian syndrome (PCOS) among young female adults<#LINE#>G.@Asha , P.A.@Mounika <#LINE#>6-9<#LINE#>2.ISCA-RJRS-2018-054.pdf<#LINE#>Department of Food and Nutrition, Smt. VHD Central Institute of Home Science, Seshadri Road, Bengaluru-560 001, Karnataka, India@Department of Food and Nutrition, Smt. VHD Central Institute of Home Science, Seshadri Road, Bengaluru-560 001, Karnataka, India<#LINE#>16/7/2018<#LINE#>20/9/2018<#LINE#>Polycystic ovarian syndrome (PCOS) is a hormonal disorder which affects the women of reproductive age where in the ovaries produce male hormones in higher level which prevents ovulation and leads to irregular menstrual cycle. There is strong association between hyperandrogenism with chronic anovulation in women causing infertility. About 5-10 per cent of women are affected worldwide. It is characterized by irregular or no menstrual periods, acne, obesity, and excess hair growth. The development of obesity amplifies PCOS in women. The study was conducted at three colleges of Bangalore city. A questionnaire was developed and validated to assess the knowledge towards PCOS. The subjects aged between 18 to 25 years were screened by taking height, weight and through BMI by random sampling. 100 overweight and obese samples were taken for the study. The subjects knowledge responses were collected. There were 37 percent overweight and 15 percent obese subjects in the age group of 21-22 years, 11 percent of overweight and 14 percent of obese subjects in the age group of 23-24 years and 10 percent of overweight and 13 percent of obese subjects in the age group of 18-20 years. More than half (56%) of the respondents age of menarche was at the age of 12 to 13 years where as 36 per cent and 8 per cent of the respondents attained their menarche at the age of 14 to 15 and 10 to 12 years respectively. 36 per cent of the subjects had irregular menstrual cycle. Majority of the samples did not have an adequate knowledge about PCOS. It is very important that all young females especially who are overweight and obese should know about the causes, risk factors, complications, diagnosis and management of the disease so that unrecognized and neglected symptoms can be introspected by the individual samples in order to prevent the degree and complications of PCOS. Nearly 79 percent of respondents of both over weight and obese young females had inadequate knowledge on PCOS whereas 21 percent of the subjects had inadequate knowledge. The results showed significant difference at 5 percent level. An adoption of active lifestyle habits, healthy dietary habits and regular physical activities help in prevention and management of PCOS among adults.<#LINE#>Thathapudi S., Kodati V., Erukkambattu J., Katragadda A., Addepally U. and Hasan Q. (2014).@Anthropometric and biochemical characteristics of polycystic ovarian syndrome in South Indian women using AES-2006 criteria.@International journal of endocrinology and metabolism, 12(1).@Yes$Nidhi R., Padmalatha V., Nagarathna R. and Amritanshu R.J. (2011).@Prevalence of polycystic ovarian syndrome in Indian adolescents.@Pediatr. Adolesc. Gynecol., 24(4), 223-227.I@Yes$Franks S. (2013).@Polycystic ovary syndrome.@Medicine, 41(10), 553-610.@No$Barber T.M., McCarthy M.I., Wass J.A.H. and Franks S. (2006).@Obesity and polycystic ovary syndrome.@Clinical endocrinology, 65(2), 137-145. https://doi.org/10.1111/ j.1365-2265.2006.02587.x@Yes$Poobalan A. and Aucott L. (2016).@Obesity among young adults in developing countries: a systematic overview.@Current obesity reports, 5(1), 2-13.@Yes$Strowitzki T., Capp E. and von Eye Corleta H. (2010).@The degree of cycle irregularity correlates with the grade of endocrine and metabolic disorders in PCOS patients.@European Journal of Obstetrics & Gynecology and Reproductive Biology, 149(2), 178-181.@Yes$Sunanda B. and Sabitha Nayak (2016).@A Study to Assess the Knowledge Regarding PCOS (Polycystic Ovarian Syndrome) among Nursing Students at NUINS.@Nitte University Journal of Health Science, 6(3), 24-25.@Yes$Manita D., Babu M. and Rastogi S. (2014).@An exploratory survey to assess the knowledge, practice and prevalence of polycystic ovarian syndrome among women attending gyne OPD of selected hospital of Delhi with a view to develop a health care package on polycystic ovarian syndrome and its management.@IOSR Journal of Nursing and Health Science (IOSRJNHS), 3(6), 39-42.@Yes
<#LINE#>The push factors of producers mango in using label as part of customer service marketing<#LINE#>Deliana@Yosini ,Fatimah @Sri ,Charina@Anne  <#LINE#>10-13<#LINE#>3.ISCA-RJRS-2018-056.pdf<#LINE#>Padjadjaran University, Jl. Raya Bandung – Sumedang Km 21, Sumedang, Indonesia@Padjadjaran University, Jl. Raya Bandung – Sumedang Km 21, Sumedang, Indonesia@Padjadjaran University, Jl. Raya Bandung – Sumedang Km 21, Sumedang, Indonesia<#LINE#>1/5/2018<#LINE#>2/8/2018<#LINE#>Mango is one of favorite fruits that almost every body like it, but consumers are often disappointed because it is not uniform quality. Producers or the farmers are interested in using label when consumer willingness to pay is higher. This fenomena is interested to study what push factors of producers mango in using label as part of customer service marketing. The research method is survey with 260 farmers using simple random sampling from 4 sub district in Cirebon such as Astanajapura, Greged, Dukupuntang and Sedong. The results of this study revealed that push factors are income, access of market, concern of quality and safety food. The farmers who get higher income, better access market, concern of quality and safety food tend to used label. The farmers believe that label is one way for better customers servive but they only used label when willlingnes to pay consumers is higher. Another factor that is not a motivating factor are family member, mango is cultivated for second priority, number of trees, and the label is not an issue when done by wholesaler or exportir. There must be the government agency to ensures that label is the quality assurance and product safe for consumption.<#LINE#>Dittmar M. (2001).@Changing colour preferences with ageing: A comparative study on younger and older native Germans aged 19–90 years.@Gerontology, 47(4), 219-226.@Yes$Deliana Y., Fatimah S. and Charina A. (2015).@Product Origin Labelling and Consumer Willingness to Pay.@Research Journal of Recent Sciences.@Yes$Wong V. and Saunders J. (2006).@Factor for Success.@37-41. doi:10.1080/09652549300000003@No$Day G.S. (1994).@The of market-drive capabilities organizations.@Journal of Marketing, 58(4), 37-52.@Yes$Coviello N.E., Brodie R.J., Danaher P.J. and Johnston W.J. (2002).@How firms relate to their markets: an empirical examination of contemporary marketing practices.@Journal of marketing, 66(3), 33-46.@Yes$Rayhan Y. and Deliana Y. (2018).@The Effectivity Of Taci Kembar ’ S Social Media Advertisement With Epic Model Approach.@Faculty of Agriculture, Padjajaran University, 14-19.@No$Payne A. and Frow P. (2005).@A strategic framework for customer relationship management.@Journal of marketing, 69(4), 167-176.@Yes$Kale S.H. (2004).@CRM failure and the seven deadly sins.@Marketing management, 13(5), 42-46.@Yes$Boulding W., Staelin R., Ehret M. and Johnston W.J. (2005).@A customer relationship management roadmap: What is known, potential pitfalls, and where to go.@Journal of marketing, 69(4), 155-166.@Yes$Wilson H., Daniel E., Mcdonald M., Wilson H. and Daniel E. (2010).@Factors for Success in Customer Relationship Management (CRM) Systems Relationship Management (CRM).@37-41.@No
@Short Communication
<#LINE#>Use of solid supported reagent in organic synthesis<#LINE#>Revika@Arora  <#LINE#>14-16<#LINE#>4.ISCA-RJRS-2018-052.pdf<#LINE#>Govt. PG College for Women, Gandhi Nagar, Jammu, J&K, India<#LINE#>11/1/2018<#LINE#>6/8/2018<#LINE#>The use of solid supported reagents is increasing, due to their tremendous potential to offer green chemical technologies. Now-a-days, silica supported acid catalysts have gained much importance due to their high activity.  Moreover, silica-supported reagents are easy to handle, less toxic, can be easily separated and reused, due to which they may play important role both in academia and industries. Silicas generally require no pre-swelling, which makes their use far simpler. As oxidative bromination of alkenes is very important in synthesizing biologically and synthetically important dibromocompounds, a simple, efficient and cost effective method has been used for the bromination of alkenes by using SiO2 -H2SO as solid heterogeneous catalyst.<#LINE#>Buu-Hoï N.P. and Lavit D. (1955).@The bromination of o-and p-hydroxyaryl ketones.@Journal of the Chemical Society (Resumed), 18-20.@Yes$Campos F., Bosch M.P. and Guerrero A. (2000).@An efficient enantioselective synthesis of (R, R)-formoterol, a potent bronchodilator, using lipases.@Tetrahedron: Asymmetry, 11(13), 2705-2717.@Yes$Das D.P. and Parida K. (2006).@Liquid Phase bromination of phenol.@Journal of Molecular Catalysis, A, 253(1), 70-78.@Yes$Butler A. and Walker J.V. (1993).@Marine haloperoxidadses.@Chemical Reviews, 93(5), 1937-1944.@Yes$Guengerich F.P. (2003).@Activation of dihaloalkanes by thiol-dependent mechanisms.@BMB Reports, 36(1), 20-27.@Yes$Prusov E., Röhm H. and Maier M.E. (2006).@Chemoenzymatic synthesis of the C10&#8722;C23 segment of dictyostatin.@Organic letters, 8(6), 1025-1028.@Yes$Sugiyama H., Yokokawa F. and Shioiri T. (2000).@Asymmetric Total Synthesis of (&#8722;)-Mycothiazole.@Organic letters, 2(14), 2149-2152.@Yes$Daniel P.T., Koert U. and Schuppan J. (2006).@Apoptolidin: induction of apoptosis by a natural product.@Angewandte Chemie International Edition, 45(6), 872-893.@Yes$Narayan R.S. and Borhan B. (2006).@Synthesis of the proposed structure of mucoxin via regio-and stereoselective tetrahydrofuran ring-forming strategies.@The Journal of organic chemistry, 71(4), 1416-1429.@Yes$Izzo I., De Caro S., De Riccardis F. and Spinella A. (2000).@Synthesis of alkylphenols and alkylcatechols from the marine mollusc Haminoea callidegenita.@Tetrahedron Letters, 41(20), 3975-3978.@Yes$Kutsumura N., Yokoyama T., Ohgiya T. and Nishiyama S. (2006).@1, 2-Dibromoalkanes into alkynes by elimination reaction under DBU conditions and their application to total synthesis of sapinofuranone B.@Tetrahedron letters, 47(25), 4133-4136.@Yes$Veisi H., Ghorbani-Vaghei R. and Zolfigol M.A. (2011).@Recent Progress in the Use of N-Halo Compounds in Organic Synthesis.@Organic Preparations and Procedures International, 43(6), 489-540.@Yes$Mestres R. and Palenzuela J. (2002).@High atomic yield bromine-less benzylic bromination.@Green Chemistry, 4(4), 314-316.@Yes$Clark J.H. (1999).@Green chemistry: challenges and opportunities.@Green Chemistry, 1(1), 1-8.@Yes$Anastas P.T. and Warner J.C. (1998).@Green Chemistry.@Theory and Practice (Oxford University Press, Oxford), 105.@Yes$Barhate N.B., Gajare A.S., Wakharkar R.D. and Bedekar A.V. (1998).@Simple and efficient chlorination and bromination of aromatic compounds with aqueous TBHP (or H2O2) and a hydrohalic acid.@Tetrahedron letters, 39(35), 6349-6350.@Yes$Rodebaugh R., Debenham J.S., Fraser-Reid B. and Snyder J.P. (1999).@Bromination of alkenyl glycosides with copper (II) bromide and lithium bromide: Synthesis, mechanism, and DFT calculations.@The Journal of organic chemistry, 64(5), 1758-1761.@Yes$Nair V., Panicker S.B., Augustine A., George T.G., Thomas S. and Vairamani M. (2001).@An efficient bromination of alkenes using cerium (IV) ammonium nitrate (CAN) and potassium bromide.@Tetrahedron, 57(34), 7417-7422.@Yes$Moriuchi T., Yamaguchi M., Kikushima K. and Hirao T. (2007).@An efficient vanadium-catalyzed bromination reaction.@Tetrahedron letters, 48(15), 2667-2670.@Yes$Barhate N.B., Gajare A.S., Wakharkar R.D. and Bedekar A.V. (1999).@Simple and practical halogenation of arenes, alkenes and alkynes with hydrohalic acid/H2O2 (or TBHP).@Tetrahedron, 55(36), 11127-11142.@Yes$Levin Y., Hamza K., Abu&#8208;Reziq R. and Blum J. (2006).@Sol&#8208;Gel Entrapped Pyridinium Hydrobromide Perbromide as a Recyclable Bromination Agent: Its Application to a One&#8208;Pot Bromination and Dehydrobromination Process.@European journal of organic chemistry, 1396-1399.@Yes$Chaudhuri M.K., Khan A.T., Patel B.K., Dey D., Kharmawophlang W., Lakshmiprabha T.R. and Mandal G.C. (1998).@An environmentally benign synthesis of organic ammonium tribromides (OATB) and bromination of selected organic substrates by tetrabutylammonium tribromide (TBATB).@Tetrahedron letters, 39(44), 8163-8166.@Yes$Muathen H.A. (2004).@Mild oxidative bromination of alkenes and alkynes with zinc bromide and lead tetraacetate.@Synthetic communications, 34(19), 3545-3552.@Yes$Kajigaeshi S., Kakinami T., Moriwaki M., Fujisaki S. and Tashiro M. (1988).@Bromination of Alkenes and Related Compounds by Use of Benzyltrimethyl ammonium Tribromide in Aprotic and Protic Solvents.@Rep. Inst. Advanced Material Study, 2(1), 87-94.@Yes$Shen Y., Atobe M., Li W. and Nonaka T. (2003).@Paired electrosynthesis of epoxides and dibromides from olefinic compounds.@Electrochimica acta, 48(8), 1041-1046.@Yes$Moghaddam F.M., Masoud N., Foroushani B.K., Saryazdi S., Ghonouei N. and Daemi E. (2013).@Silica-supported DABCO-tribromide: A recoverable reagent for oxidation of alcohols to the corresponding carbonyl compounds.@Scientia Iranica, 20(3), 598-602.@Yes$Kapferer P. and Vasella A. (2004).@Electrophilic Bromination of N&#8208;Acylated Cyclohex&#8208;3&#8208;en&#8208;1&#8208;amines: Synthesis of 7&#8208;Azanorbornanes.@Helvetica chimica acta, 87(11), 2764-2789.@Yes