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Application of Solid State Fermentation Technology in Environmental Cleanup and Lactic Acid Production

Author Affiliations

  • 1Faculty of life science, Department of Biotechnology, AKS University, Satna, MP, INDIA
  • 2Department of Polymer and Process Engineering, Indian Institute of Technology Roorkee, INDIA

Res. J. Recent Sci., Volume 4, Issue (ISC-2014), Pages 65-72, (2015)


Solid state fermentation technology utilizes various agricultural wastes, forestry wastes and dairy, food and pulp and paper industries industry. Several reactor designs operating with solid state fermentation technology include packed bed reactor, fluidized bed reactor, rotating drum reactor, and stirred tank reactor, rocking drum reactor, stirred drum reactor and Zymotis reactor configurations. The SSF technology helps in management of solid and liquid wastes integrated with inexpensive biochemical production. The present paper includes practical data on lactic acid production by solid state fermentation technology utilizing wheat bran bed material and dairy waste whey and also highlights some of the technologies applicable for maximizing the biochemical production by SSF technology.


  1. Ghosh M.K. and Ghosh U.K., Utilization of pine needles as bed material in solid state fermentation for production of lactic acid by Lactobacillus strains, BioRes., 6(2),1556-1575, (2011), 65-72 (2015)
  2. Kaur H., Dutt D. and Tyagi C.H., Production of novel alkali tolerant xylanases from Coprinopsis cinerea HK-1 NFCCI-2032, BioRes., 6(2), 1376-1391, (2011)
  3. Verma N., Bansal M.C. and Kumar V., Pea peel waste: A lignocellulosic waste and its utility in cellulase production by Trichoderma reesi under solid state cultivation, BioRes., 6(2), 1505-1519, (2011)
  4. Mitchell D.A., Krieger N. and Berovic M., Solid state fermentation bioreactors-fundamentals of design and operation, 33-44, (2005)
  5. Adsul M.G., Varma A.J. and Gokhale D.V., Lactic acid production from waste sugarcane bagasse derived cellulose, Green Chem.,, 58-62, (2007)
  6. Adradosa B.P., Choteborskab P., Galbea M. and Zacchia G., Ethanol production from non- starch carbohydrates of wheat bran, Biores. Technol., 96(7), 843-850, (2005)
  7. Trivedi T.P., Handbook of Agriculture, Wheat, thedition, 845-857, (2008)
  8. Sun X., Liu Z., Qu Y. and Li X., The Effect of wheat bran composition on production of biomass-hydrolyzing enzymes by Penicillium decumbens, Appl. Biochem.Biotechnol.,146, 119- 128, (2008)
  9. Naveena B.J., Vishnu C., Mohammed A. and Reddy G., Wheat bran an inexpensive substrate for production of lactic acid in solid state fermentation by Lactobacillus amylophilus GV6: Optimization of fermentation conditions, J. of Scientific and Ind. Res., 62(5), 453-456, (2003)
  10. John R.P., Nampoothiri K.M. and Pandey A., Simultaneous saccharification and L-(+)- lactic acid fermentation of protease treated wheat bran using mixed culture of lactobacilli, Biotech. Lett., 28(22), 1823-1826, (2006a)
  11. Kumar P., Yadava R.K., Gollen B., Kumar S., Verma R.K., and Yadav S., Nutritional contents and medicinal properties of wheat: a review, Life Sc. and Medicine Res., 2011 LSMR-22, 1-10, (2011)
  12. Available online at: 12.Murphy J.C. and Jones D.B., Proteins of wheat bran III, The nutritive properties of the proteins of wheat bran, J. of Biol. Chem., 69, 85-99, (1926)
  13. Bullerman L.B. and Berry E.C., Use of cheese whey for vitamin B12 production Growth studies and dry weight activity, Applied Microbiol.,14(3), 358-360, (1966)
  14. Ghasemi M., Ghasem N., Rahimnejad M., Beigi P.A., Sedighi M. and Hashemiyeh B., Effect of different media on production of lactic acid from whey by Lactobacillus bulgaricus, African J. ofBiotech, 8(1), 81-84, (2009)
  15. Aggarwal L., Dutt K., Meghvanshi G.K. and Saxena R.K., Anaerobic fermentative production of lactic acid using cheese whey and corn steep liquor, Biotech. Letters, 30, 631- 635, (2008)
  16. Panesar P.S., kennedy J.F., Gandhi D.N. and Bunko K., Bio-utilization of whey for lactic acid production, Food Chem., 105(1),1-14, (2007)
  17. Vasantha T., Enymatic quantification of total starch in plant products(Holm Method), E2.2.4, Current Protocols in Food Anal. Chem., E2.2.4-E2.2.9, (2001)
  18. Goncalves A.R., Ruzene D.S., Moriya R.Y. and Oliveria L.R.M., Pulping of sugarcane bagasse and straw and biobleaching of the pulps: Conditions, parameters and recycling of enzymes, 59th Appita Conference, Auckland, New Zealand, May 16-19, (2005)
  19. Bradford MM., A rapid and sensitive for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding, Anal. Biochem, 72, 248-254, (1976)
  20. Nickerson T.A., Vujicic I.F. and Lin A.Y., Colorimetric estimation of lactose and its hydrolytic products, Journal Of Dairy Science, 59, 386-390, (1976)
  21. Taylor K.A.C.C., A simple colorimetric assay for muramic acid and lactic acid, Appl. Biochem. Biotechnol., 56, 49-58, (1996)
  22. John R.P., Nampoothiri K.M., Nair A.S. and Pandey A., L(+) lactic acid production using Lactobacillus casei in solid state fermentation, Biotech. Letters,27(21), 1685-1688, (2006b)
  23. Kumar S., Upadhyaya, and J.S. Negi, Y.S., Preparation of nano particles from corn cobs by chemical treatment methods, BioRes., 5(2), 1292-1300, (2010a)
  24. Carvalheiro F., Duarte L.C. and Girio F.M., Hemicellulose biorefineries: a review on biomass pretreatments, J. of Scientific and Ind. Res., 67,849-864, (2008)
  25. Goyal N. and Gandhi D.N., Whey, a carrier of probiotics against diarrhoea, Dairy Sc. and Food Tech. (online), (2008)
  26. Kumar S., Negi Y.S. and Upadhyaya J.S., Studies on characterization of corn cob based nanoparticles, Advanced Materials Letters, 1(3), 246-253, (2010b)
  27. Hasan S.H. and Ranjan D., Agro-industrial Waste: A low cost option for the biosorptive remediation of selenium anions, Ind. and Engg. Chem. Res.,49(19), 8927-8934, (2010)
  28. Barron C., Parker M.L., Mills E.N.C., Ruau X. and Wilson R.H., FTIR imaging of wheat endosperm cell walls insitu reveals compositional and architectural heterogeneity related to grain hardness, Planta, 220(5), 667-677, (2005)