@Research Paper
<#LINE#>Educational aspiration of adolescent learners: A comparative study in Assam, India<#LINE#>Rantu @Gohain <#LINE#>1-6<#LINE#>1.ISCA-RJRS-2021-022.pdf<#LINE#>Department of Education, Sibsagar Girls’ College (Sivasagar), Assam, India<#LINE#>6/9/2021<#LINE#>23/4/2022<#LINE#>Educational aspiration refers to the educational goals a person sets for himself. Level of educational aspiration means where and how an individual sets his targets for achievement. The present study intends to have a comparative study of educational aspiration between boys’ and girls’ adolescent learners in terms of gender, locality, involvement of teachers and parental encouragement. Descriptive survey method was employed. 200 samples were collected employing stratified random sampling technique. Data were analyzed using statistical techniques like Mean, SD, t-test and Chi-square (x2). The results showed that there is no significant difference of level of educational aspiration between boys’ and girls’ higher secondary students of classes XI and XII with respect to gender, locality and involvement of teachers. But significant difference was found between them in case of parental encouragement at 0.01 level of significance.  This research is expected to disseminate information to the stakeholders to pay more attention to increase level of educational aspiration of adolescent learners.<#LINE#>Khoo, S. & Ainsley, J. (2005).@Attitudes, Intentions and Participation: Longitudinal Survey of Australian Youth.@Research Report No. 41.@Yes$Boyd, G. F. (1952).@The levels of aspiration of white and Negro children in a non-segregated elementary school.@The Journal of Social Psychology, 36(2), 191-196.@Yes$Fraser, M. and Garg, R. (2014).@Educational Aspirations, Encyclopedia of Adolescence.@DOI: https://doi.org/10. 1007/978-4419-1695-2@No$Bohon, S. A., Johnson, M. K., & Gorman, B. K. (2006).@College aspirations and expectations among Latino adolescents in the United States.@Social problems, 53(2), 207-225.@Yes$Chawla, M. (2018).@A study of educational aspirations of secondary school students in relation to their achievement scores.@International Journal of Research in Social Sciences, 8(4), 872-880.@Yes$Marjoribanks, K. (1997).@Family background, social and academic capital, and adolescents@Social Psychology of Education, 2(2), 177-197.@Yes$Hall, G. S. (1904).@Adolescence, Its Psychology and Its Relations to Physiology, Anthropology, Sociology, Sex, Crime, Religion, and Education.@by G. Stanley Hall... S. Appleton.@Yes$Wilson, P. M., & Wilson, J. R. (1992).@Environmental influences on adolescent educational aspirations: A logistic transform model.@Youth & Society, 24(1), 52-70.@Yes$Mau, W. C., & Bikos, L. H. (2000).@Educational and vocational aspirations of minority and female students: A longitudinal study.@Journal of counseling & development, 78(2), 186-194.@Yes$Kishor, V. (2014).@Parental encouragement.@Research Journal of Humanities and Social Sciences, 5(2), 176-179.@Yes$Bashir, L., & Kaur, R. (2017).@A study on interrelation of educational aspiration with school environment of secondary school students.@Educational Quest-An International Journal of Education and Applied Social Sciences, 8(spl), 269-275.@Yes$Salgotra, A. K., & Roma, K. (2018).@Educational aspiration and socio-economic status among secondary school students.@Journal of Humanities and Social Science, 23(3), 25-29.@Yes$Chawla, M. (2018).@A study of educational aspirations of secondary school students in relation to their achievement scores.@International Journal of Research in Social Sciences, 8(4), 872-880.@Yes$Raja, S., & Pandian, U. (2016).@A study on level of educational aspiration of high school students.@International Journal of Science and Research, 7(12), 859-861.@Yes$Debnath, M and Singh, A.K. (2020).@A Study on Educational Aspiration of Secondary level School Students in relation to their Gender, Locality and Academic Achievement.@Mukt Shabd Journal, IX(IV), 4278-85.@No$Quaglia, R. (1989).@Student Aspirations: A Critical Dimension in Effective Schools.@Research in rural education, 6(2), 7-9.@Yes$Chawla, M. (2018).@A study of educational aspirations of secondary school students in relation to their achievement scores.@International Journal of Research in Social Sciences, 8(4), 872-880.@Yes$George, J. (2014).@Educational aspiration of higher secondary school students: A comparative study based on certain demographic variables.@The International Journal of Humanities and Social Studies, 2(1), 78-81.@Yes$Bashir, L., & Kaur, R. (2017).@A study on interrelation of educational aspiration with school environment of secondary school students.@Educational Quest-An International Journal of Education and Applied Social Sciences, 8(spl), 269-275.@Yes
<#LINE#>Status of retail fish markets of Choryasi taluka and Surat city (India) with reference to bacteriological examination of fishes<#LINE#>Niharika P. @Shah <#LINE#>7-11<#LINE#>2.ISCA-RJRS-2021-024.pdf<#LINE#>Department of Aquatic Biology, Veer Narmad South Gujarat University, Udhana Magdalla Road, Surat-395007, Gujarat, India<#LINE#>5/9/2021<#LINE#>6/3/2022<#LINE#>Quality of fish is an important criteria for human health. The pathogens like Escherichia coli and Klebsiella pneumoniae can survive and multiply in fish, transferred in to humans from fish used as food and cause food poisoning, diarrhoea, meningitis and septicaemia. Taking into consideration, bacteriological analyses were done to know the quality of fishes sold at retail fish markets of Choryasi Taluka and Surat city. Fish samples were collected from fish markets for enumeration of the total viable count (TVC) and identification of bacteria. Bacteriological analyses of fresh fish samples (Mugil parsia and Stromateus cinereus) showed higher bacterial load with pathogenic bacteria which crossed permissible limit (5×105 CFU/g) except the case of Mugil parsia from vendors of Gabheni village. The fishes were contaminated with Escherichia coli and Klebsiella pneumoniae indicating poor hygiene and sanitary condition of the retail fish markets. Apart from this, A innovative trend in live fish marketing was observed in retail fish market of Katargam to overcome from problems like contaminated and poor quality fishes. Fresh water fishes collected from this live fish market were completely free from bacteria indicating good quality fishes available in the market.<#LINE#>Emikpe, B. O., Adebisi, T., & Adedeji, O. B. (2011).@Bacteria load on the skin and stomach of Clarias gariepinus and Oreochromis niloticus from Ibadan, South West Nigeria: Public health implications.@Journal of Microbiology and Biotechnology Research, 1(1), 52-59.@Yes$Maehre, H. K., Jensen, I. J., Elvevoll, E. O., & Eilertsen, K. E. (2015).@ω-3 fatty acids and cardiovascular diseases: Effects, mechanisms and dietary relevance.@International journal of molecular sciences, 16(9), 22636-22661.@Yes$Boucher, O., Burden, M. J., Muckle, G., Saint-Amour, D., Ayotte, P., Dewailly, E., ... & Jacobson, J. L. (2011).@Neurophysiologic and neurobehavioral evidence of beneficial effects of prenatal omega-3 fatty acid intake on memory function at school age.@The American journal of clinical nutrition, 93(5), 1025-1037.@Yes$Huss, H. H. (1997).@Control of indigenous pathogenic bacteria in seafood.@Food control, 8(2), 91-98.@Yes$Novotny, L., Dvorska, L., Lorencova, A., Beran, V., & Pavlik, I. (2004).@Fish: a potential source of bacterial pathogens for human beings.@Veterinarni Medicina, 49(9), 343-358.@Yes$Alikunhi, N. M., Batang, Z. B., AlJahdali, H. A., Aziz, M. A., & Al-Suwailem, A. M. (2017).@Culture-dependent bacteria in commercial fishes: Qualitative assessment and molecular identification using 16S rRNA gene sequencing.@Saudi Journal of Biological Sciences, 24(6), 1105-1116.@Yes$Karthiga Rani, M., Chelladurai, G., & Jayanthi, G. (2016).@Isolation and identification of bacteria from marine market fish Scomberomorus guttatus (Bloch and Schneider, 1801) from Madurai district, Tamil Nadu, India.@Journal of Parasitic Diseases, 40, 1062-1065.@Yes$Surendran, P. K., Thampuran, N., Nambiar, V. N., & Lalitha, K. V. (2006).@Laboratory manual on microbiological examination of seafood.@CIFT, Cochin.@Yes$Patel, R. J. and Patel, K. R. (2000).@Experimental microbiology.@Aditya, Ahemdabad, India, 1, 95-127.@No$Cheesbrough, M. 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(2010).@The occurrence of Escherichia coli in fish samples isolated from different ponds of Nadia District, West Bengal, India.@Internet Journal of Food Safety, 12, 181-186.@Yes$Karthiga Rani, M., Chelladurai, G., & Jayanthi, G. (2016).@Isolation and identification of bacteria from marine market fish Scomberomorus guttatus (Bloch and Schneider, 1801) from Madurai district, Tamil Nadu, India.@Journal of Parasitic Diseases, 40, 1062-1065.@Yes$Podschun, R., & Ullman, U. (1998).@Klebsiella sp. as nosocomial pathogens Protein.@Journal of Antimicrobial Agents and Chemotherapy, 41, 563-569.@Yes$Amin, A., Ghumro, P. B., Hussain, S., & Hameed, A. (2009).@Prevalence of antibiotic resistance among clinical isolates of Klebsiella pneumoniae isolated from a Tertiary Care Hospital in Pakistan.@Malaysian Journal of Microbiology, 5(2), 81-86.@Yes$Zambuchini, B., Fiorini, D., Verdenelli, M. C., Orpianesi, C., & Ballini, R. (2008).@Inhibition of microbiological activity during sole (Solea solea L.) chilled storage by applying ellagic and ascorbic acids.@LWT-Food Science and Technology, 41(9), 1733-1738.@Yes$Newaj, A., Mutani, A., Ramsubhag, A. and Adesiyun, A. (2008).@Prevalence of bacterial pathogens and their anti-microbial resistance in Tilapia and their pond water in Trinidad.@Zoonoses Public Health, 55(4), 206-213.@Yes$Zheng, D. K., Mai, S., Liu, C., Limin, Z., Liufu, W.,  Xu, B. and Zhang, W. (2004).@Effect of temperature and salinity on virulence of Edwardsiellatarda to Japanese flounder, Paralichthysolivaceus (Temminck et Schlegel).@Aqua. Res., 35:494–500.@Yes$Sekar, V. T., Santiago, K., Vijayan, S., Alavandi, V., Raj, J., Rajan, M., Sanjuktha and Kalaimani, N. (2002).@Involvement of Enterobacter cloacae in the mortality of the fish, Mugil cephalus. Lett.@Appl. Microbiol., 46(6), 667-672.@Yes$Lopez-Sabater, E.I., Rodriguez-Jerez, J.J., Hernandez-Herrero, M., Roig-Sagues, A.X. and Mora-Ventura, M.A.T. (1996).@Sensory quality and histamine formation during controlled decomposition of tuna (Thunnus thynnus).@Journal of Food Protection, 59, 167-174.@Yes$Kim, S.H., Field, K.G., Chang, D.S. and Wei, C.I. (2001).@Identification of bacteria crucial to histamine accumulation in Pacific mackerel during storage.@Journal of Food Protection, 64, 1556-1564.@Yes$Cemek, M., Akkaya, L., Bulut, S., Konuk, M. and Birdane, Y.O. (2006).@Histamine, nitrate and nitrite content of meat products marketed in Western Anatolia, Turkey.@Journal of Animal and Veterinary Advances, 5, 1109-1112.@Yes$Kim, S. H., Ben-Gigirey, B., Barros-Velázquez, J., Price, R. J., & An, H. (2000).@Histamine and biogenic amine production by Morganella morganii isolated from temperature-abused albacore.@Journal of Food Protection, 63(2), 244-251.@Yes$Caldreich, E.E. and Clark, N.A. (1966).@Bacterial pollution indictors in the intestinal track of fresh water fish.@Journal of Applied Microbiology, 41, 429-437.@Yes$Fapohunda, A.O., MacMillan, K.W., Marshall, D.L. and Waites, W.M. (1994).@Growth of selected cross contaminating bacterial pathogens on beef and fish at 15 and 35°C.@Journal of Food Protection, 57, 40-337.@Yes$Ampofo, J.A. and Clerk, G.C. (2010).@Diversity of bacteria contaminants in tissues of fish cultured in organic waste fertilized ponds: Health implications.@The Open Fish Science Journal, 3, 142-146.@Yes$Ananthanarayan, R. and Paniker, J. (2009).@Textbook of microbiology.@Universities press Pvt. Ltd., pp 279.@No$Pathan, J., Tandel J., Vadhel, N., Kumar, S. and Chauhan, Y. 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@Review Paper
<#LINE#>Exploring possible SARS-CoV2 vaccines using plant biotechnology<#LINE#>Sangjukta @Biswas,Minakshi @Mahajan,Snehangshu @Das <#LINE#>12-25<#LINE#>3.ISCA-RJRS-2021-011.pdf<#LINE#>Department of Botany, Fergusson College, Pune-411004, India@Department of Botany, Fergusson College, Pune-411004, India@Department of Botany, Shivaji University, Kolhapur-416004, India<#LINE#>13/7/2021<#LINE#>18/3/2022<#LINE#>This decade began with an unprecedented crisis. The Severe Acute Respiratory Syndrome Corona virus 2 (SARS-CoV2) global pandemic capsized our lives and completely overturned the global infrastructure where healthcare and international economics were affected the most. Due to a high transmissible and mutation rate coupled with a staggering mortality rate, this virus has outdone its closely related precursors – MERS/SARS-CoV in terms of lethality. Scientists and renowned pharmaceutical companies have come under immense pressure to mitigate this problem as soon as possible, for which they have been compelled to think out of the box, as well. The construction and mass production of an efficient and accurate vaccine is the global objective now. Scientists and academicians from all walks of science have come together in this joint venture. During this desperate time, plant science has recently been gaining the spotlight via its production of transgenic plants by stable/transient expression of recombinant proteins, which poses to be a ludicrous technology, primarily due to its high-cost effectiveness. Several established pharmaceutical companies have already started to make capital out of this technology. This review paper aims to highlight the plant system as a stable, upcoming, and efficient manufacturing and delivery system of vaccines.<#LINE#>Wu, D., Wu, T., Liu, Q., & Yang, Z. (2020).@The SARS-CoV-2 outbreak: what we know.@International journal of infectious diseases, 94, 44-48.@Yes$Cucinotta D and Vanelli M. (2020).@WHO Declares COVID-19 a Pandemic.@Acta Biomed. Mar 19; 91(1), 157-160. doi: 10.23750/abm.v91i1.9397.@Yes$Shin, M.D., Shukla, S., Chung, Y.H. et al. (2020).@COVID-19 vaccine development and a potential nanomaterial path forward.@Nat. Nanotechnol. 15, 646–655 (2020).@Yes$Weiss, S. R., & Leibowitz, J. L. (2011).@Coronavirus pathogenesis.@Advances in virus research, 81, 85-164.@Yes$Yang, D., & Leibowitz, J. L. (2015).@The structure and functions of coronavirus genomic 3′ and 5′ ends.@Virus research, 206, 120-133.@Yes$Drosten, C., Günther, S., Preiser, W., Van Der Werf, S., Brodt, H. R., Becker, S., ... & Doerr, H. W. (2003).@Identification of a novel coronavirus in patients with severe acute respiratory syndrome.@New England journal of medicine, 348(20), 1967-1976.@Yes$Zaki, A. M., Van Boheemen, S., Bestebroer, T. M., Osterhaus, A. D., & Fouchier, R. A. (2012).@Isolation of a novel coronavirus from a man with pneumonia in Saudi Arabia.@New England Journal of Medicine, 367(19), 1814-1820.@Yes$Yao, H., Song, Y., Chen, Y., Wu, N., Xu, J., Sun, C., Zhang, J., Weng, T., Zhang, Z., Wu, Z., Cheng, L., Shi, D., Lu, X., Lei, J., Crispin, M., Shi, Y., Li, L. and Li, S. (2020).@Molecular architecture of the SARS-CoV-2 virus.@Cell, 183(3), 730-738@Yes$Kim, J. M. et al. (2020).@Identification of coronavirus isolated from a patient in Korea with COVID-19.@Osong Public Health Res. Perspect., 11, 3–7.@Yes$Li, F. (2016).@Structure, function, and evolution of coronavirus spike proteins.@Annual review of virology, 3, 237-261.@Yes$Kirchdoerfer, R. N., Cottrell, C. A., Wang, N., Pallesen, J., Yassine, H. M., Turner, H. L., ... & Ward, A. B. (2016).@Pre-fusion structure of a human coronavirus spike protein.@Nature, 531(7592), 118-121.@Yes$Walls, A. C., Tortorici, M. A., Bosch, B. J., Frenz, B., Rottier, P. J., DiMaio, F., ... & Veesler, D. (2016).@Cryo-electron microscopy structure of a coronavirus spike glycoprotein trimer.@Nature, 531(7592), 114-117.@Yes$Beniac, D. R., Andonov, A., Grudeski, E., & Booth, T. F. (2006).@Architecture of the SARS coronavirus prefusion spike.@Nature structural & molecular biology, 13(8), 751-752.@Yes$Li, F., Berardi, M., Li, W., Farzan, M., Dormitzer, P. R., & Harrison, S. C. (2006).@Conformational states of the severe acute respiratory syndrome coronavirus spike protein ectodomain.@Journal of virology, 80(14), 6794-6800.@Yes$Perlman, S. (2020).@Another decade, another coronavirus.@New England Journal of Medicine, 382(8), 760-762.@Yes$Zhou, P., Yang, X. L., Wang, X. G., Hu, B., Zhang, L., Zhang, W., ... & Shi, Z. L. (2020).@A pneumonia outbreak associated with a new coronavirus of probable bat origin.@Nature, 579(7798), 270-273.@Yes$Cheng, Z. J., & Shan, J. (2020).@2019 Novel coronavirus: where we are and what we know.@Infection; 48(2), 155-63.@Yes$Farah, S., Atkulwar, A., Praharaj, M. R., Khan, R., Gandham, R., & Baig, M. (2020).@Phylogenomics and phylodynamics of SARS-CoV-2 genomes retrieved from India.@Future Virology, 15(11), 747-753.@Yes$WHO (2021).@Coronavirus (COVID 19) Dashboard.@https://covid19.who.int/(accessed on 11th June 2021)@Yes$Wrapp, D., Wang, N., Corbett, K. S., Goldsmith, J. A., Hsieh, C. L., Abiona, O., ... & McLellan, J. S. (2020).@Cryo-EM structure of the 2019-nCoV spike in the prefusion conformation.@Science, 367(6483), 1260-1263.@Yes$Andersen, K. G., Rambaut, A., Lipkin, W. I., Holmes, E. C., & Garry, R. F. (2020).@The proximal origin of SARS-CoV-2.@Nature medicine, 26(4), 450-452.@Yes$Benvenuto, D., Giovanetti, M., Ciccozzi, A., Spoto, S., Angeletti, S., & Ciccozzi, M. (2020).@The 2019‐new coronavirus epidemic: evidence for virus evolution.@Journal of medical virology, 92(4), 455-459.@Yes$Yuan, M., Wu, N. C., Zhu, X., Lee, C. C. D., So, R. T., Lv, H., ... & Wilson, I. A. (2020).@A highly conserved cryptic epitope in the receptor binding domains of SARS-CoV-2 and SARS-CoV.@Science, 368(6491), 630-633.@Yes$Yan, R., Zhang, Y., Li, Y., Xia, L., Guo, Y., & Zhou, Q. (2020).@Structural basis for the recognition of SARS-CoV-2 by full-length human ACE2.@Science, 367(6485), 1444-1448.@Yes$Guglielmo, L. (2020).@Epitopes for a 2019-nCoV vaccine.@Cellular & Molecular Immunology, 17(5), 539-540.@Yes$Grifoni, A., Sidney, J., Zhang, Y., Scheuermann, R. H., Peters, B., & Sette, A. (2020).@A sequence homology and bioinformatic approach can predict candidate targets for immune responses to SARS-CoV-2.@Cell host & microbe, 27(4), 671-680.@Yes$Baruah, V., & Bose, S. (2020).@Immunoinformatics‐aided identification of T cell and B cell epitopes in the surface glycoprotein of 2019‐nCoV.@Journal of medical virology, 92(5), 495-500.@Yes$Ahmed, S. F., Quadeer, A. A., & McKay, M. R. (2020).@Preliminary identification of potential vaccine targets for the COVID-19 coronavirus (SARS-CoV-2) based on SARS-CoV immunological studies.@Viruses, 12(3), 254.@Yes$Enjuanes, L., Zuñiga, S., Castaño-Rodriguez, C., Gutierrez-Alvarez, J., Canton, J., & Sola, I. (2016).@Molecular basis of coronavirus virulence and vaccine development.@Advances in virus research, 96, 245-286.@Yes$Song, Z., Xu, Y., Bao, L., Zhang, L., Yu, P., Qu, Y., ... & Qin, C. (2019).@From SARS to MERS, thrusting coronaviruses into the spotlight.@Viruses, 11(1), 59.@Yes$Enjuanes, L., Almazán, F., Sola, I., & Zuñiga, S. (2006).@Biochemical aspects of coronavirus replication and virus-host interaction.@Annu. Rev. Microbiol., 60, 211-230.@Yes$Ward, B. J., Gobeil, P., Séguin, A., Atkins, J., Boulay, I., Charbonneau, P. Y., ... & Landry, N. (2021).@Phase 1 randomized trial of a plant-derived virus-like particle vaccine for COVID-19.@Nature medicine, 27(6), 1071-1078.@Yes$Perlman, S., & Netland, J. (2009).@Coronaviruses post-SARS: update on replication and pathogenesis.@Nature reviews microbiology, 7(6), 439-450.@Yes$Shin, M. D., Shukla, S., Chung, Y. H., Beiss, V., Chan, S. K., Ortega-Rivera, O. A., ... & Steinmetz, N. F. (2020).@COVID-19 vaccine development and a potential nanomaterial path forward.@Nature nanotechnology, 15(8), 646-655.@Yes$Hiatt, A., Caffferkey, R., & Bowdish, K. (1989).@Production of antibodies in transgenic plants.@Nature, 342(6245), 76-78.@Yes$Takeyama, N., Kiyono, H., & Yuki, Y. (2015).@Plant-based vaccines for animals and humans: recent advances in technology and clinical trials.@Therapeutic advances in vaccines, 3(5-6), 139-154.@Yes$Laere, E., Ling, A. P. K., Wong, Y. P., Koh, R. Y., Mohd Lila, M. A., & Hussein, S. (2016).@Plant-based vaccines: production and challenges.@Journal of Botany.@Yes$Naderi, S., & Fakheri, B. (2015).@Overview of plant-based vaccines.@Research Journal of Fisheries and Hydrobiology, 10(10), 275-289.@Yes$Gleba, Y. Y., Tusé, D., & Giritch, A. (2013).@Plant viral vectors for delivery by Agrobacterium.@Plant viral vectors, 155-192.@Yes$Peyret, H., & Lomonossoff, G. P. (2013).@The pEAQ vector series: the easy and quick way to produce recombinant proteins in plants.@Plant molecular biology, 83, 51-58.@Yes$Shoji, Y., Farrance, C. E., Bautista, J., Bi, H., Musiychuk, K., Horsey, A., ... & Yusibov, V. (2012).@A plant‐based system for rapid production of influenza vaccine antigens.@Influenza and other respiratory viruses, 6(3), 204-210.@Yes$Qiu, X., Wong, G., Audet, J., Bello, A., Fernando, L., Alimonti, J. B., ... & Kobinger, G. P. (2014).@Reversion of advanced Ebola virus disease in nonhuman primates with ZMapp.@Nature, 514(7520), 47-53.@Yes$Shohag, M. J. I., Khan, F. Z., Tang, L., Wei, Y., He, Z., & Yang, X. (2021).@COVID-19 crisis: how can plant biotechnology help?.@Plants, 10(2), 352.@Yes$Buyel, J. F., & Fischer, R. (2012).@Predictive models for transient protein expression in tobacco (Nicotiana tabacum L.) can optimize process time, yield, and downstream costs.@Biotechnology and bioengineering, 109(10), 2575-2588.@Yes$Xu, S., Gavin, J., Jiang, R., & Chen, H. (2017).@Bioreactor productivity and media cost comparison for different intensified cell culture processes.@Biotechnology Progress, 33(4), 867-878.@Yes$Ma, J. K. C., Drossard, J., Lewis, D., Altmann, F., Boyle, J., Christou, P., ... & Fischer, R. (2015).@Regulatory approval and a first‐in‐human phase I clinical trial of a monoclonal antibody produced in transgenic tobacco plants.@Plant biotechnology journal, 13(8), 1106-1120.@Yes$Sack, M., Rademacher, T., Spiegel, H., Boes, A., Hellwig, S., Drossard, J., ... & Fischer, R. (2015).@From gene to harvest: insights into upstream process development for the GMP production of a monoclonal antibody in transgenic tobacco plants.@Plant biotechnology journal, 13(8), 1094-1105.@Yes$Holtz, B. R., Berquist, B. R., Bennett, L. D., Kommineni, V. J., Munigunti, R. K., White, E. L., ... & Marcel, S. (2015).@Commercial‐scale biotherapeutics manufacturing facility for plant‐made pharmaceuticals.@Plant biotechnology journal, 13(8), 1180-1190.@Yes$Kaper, J. B., & Cobon, G. S. (2004).@New generation vaccines (No. 16024).@M. M. Levine, & G. C. Woodrow (Eds.). New York;: Marcel Dekker.@Yes$Rybicki, E. P. (2009).@Plant-produced vaccines: promise and reality.@Drug discovery today, 14(1-2), 16-24.@Yes$Gomord, V., Fitchette, A. C., Menu‐Bouaouiche, L., Saint‐Jore‐Dupas, C., Plasson, C., Michaud, D., & Faye, L. (2010).@Plant‐specific glycosylation patterns in the context of therapeutic protein production.@Plant biotechnology journal, 8(5), 564-587.@Yes$Shahid, N., & Daniell, H. (2016).@Plant-based oral vaccines against zoonotic and non-zoonotic diseases.@Plant Biotechnology Journal, 14(11), 2079–2099. doi:10.1111/pbi.12604@Yes$Naderi, S., & Fakheri, B. (2015).@Overview of plant-based vaccines.@Research Journal of Fisheries and Hydrobiology, 10(10), 275-289.@Yes$Saxena, J., & Rawat, S. (2014).@Edible vaccines.@Advances in biotechnology, 207-226.@Yes$Vasil, I. K., & Vasil, V. (2006).@Transformation of wheat via particle bombardment.@Plant Cell Culture Protocols, 273-283.@Yes$Verma, D., & Daniell, H. (2007).@Chloroplast vector systems for biotechnology applications.@Plant physiology, 145(4), 1129-1143.@Yes$Kamarajugadda, S., & Daniell, H. (2006).@Chloroplast-derived anthrax and other vaccine antigens: their immunogenic and immunoprotective properties.@Expert Review of Vaccines, 5(6), 839-849.@Yes$Cerovska, N., Hoffmeisterova, H., Moravec, T., Plchova, H., Folwarczna, J., Synkova, H., ... & Smahel, M. (2012).@Transient expression of Human papillomavirus type 16 L2 epitope fused to N-and C-terminus of coat protein of Potato virus X in plants.@Journal of biosciences, 37, 125-133.@Yes$Matić, S., Rinaldi, R., Masenga, V., & Noris, E. (2011).@Efficient production of chimeric human papillomavirus 16 L1 protein bearing the M2e influenza epitope in Nicotiana benthamiana plants.@BMC biotechnology, 11, 1-12.@Yes$Ravin, N. V., Kotlyarov, R. Y., Mardanova, E. S., Kuprianov, V. V., Migunov, A. I., Stepanova, L. A., ... & Skryabin, K. G. (2012).@Plant-produced recombinant influenza vaccine based on virus-like HBc particles carrying an extracellular domain of M2 protein.@Biochemistry (Moscow), 77, 33-40.@Yes$Shoji, Y., Farrance, C. E., Bautista, J., Bi, H., Musiychuk, K., Horsey, A., ... & Yusibov, V. (2012).@A plant‐based system for rapid production of influenza vaccine antigens.@Influenza and other respiratory viruses, 6(3), 204-210.@Yes$D’Aoust, M. A., Couture, M. M. J., Charland, N., Trépanier, S., Landry, N., Ors, F., & Vézina, L. P. (2010).@The production of hemagglutinin‐based virus‐like particles in plants: a rapid, efficient and safe response to pandemic influenza.@Plant biotechnology journal, 8(5), 607-619.@Yes$Leuzinger, K., Dent, M., Hurtado, J., Stahnke, J., Lai, H., Zhou, X., & Chen, Q. (2013).@Efficient agroinfiltration of plants for high-level transient expression of recombinant proteins.@Journal of Visualized Experiments, (77), e50521.@Yes$Wirz, H., Sauer-Budge, A. F., Briggs, J., Sharpe, A., Shu, S., & Sharon, A. (2012).@Automated production of plant-based vaccines and pharmaceuticals.@Journal of laboratory automation, 17(6), 449-457.@Yes$Gleba, Y., Marillonnet, S., & Klimyuk, V. (2004).@Engineering viral expression vectors for plants: the ‘full virus’ and the ‘deconstructed virus’ strategies.@Current opinion in plant biology, 7(2), 182-188.@Yes$Scotti, N., & Rybicki, E. P. (2013).@Virus-like particles produced in plants as potential vaccines.@Expert review of vaccines, 12(2), 211-224.@Yes$Rybicki, E. P. (2014).@Plant-based vaccines against viruses.@Virology journal, 11, 1-20.@Yes$Peyret, H., & Lomonossoff, G. P. (2013).@The pEAQ vector series: the easy and quick way to produce recombinant proteins in plants.@Plant molecular biology, 83, 51-58.@Yes$Sainsbury, F., Thuenemann, E. C., & Lomonossoff, G. P. (2009).@pEAQ: versatile expression vectors for easy and quick transient expression of heterologous proteins in plants.@Plant biotechnology journal, 7(7), 682-693.@Yes$Rosales-Mendoza, S., Márquez-Escobar, V. A., González-Ortega, O., Nieto-Gómez, R., & Arévalo-Villalobos, J. I. (2020).@What does plant-based vaccine technology offer to the fight against COVID-19?.@Vaccines, 8(2), 183.@Yes$Tang, X., Wu, C., Li, X., Song, Y., Yao, X., Wu, X., ... & Lu, J. (2020).@On the origin and continuing evolution of SARS-CoV-2.@National science review, 7(6), 1012-1023.@Yes$de Jong, J. M., Schuurhuis, D. H., Ioan-Facsinay, A., van der Voort, E. I., Huizinga, T. W., Ossendorp, F., ... & Verbeek, J. S. (2006).@Murine Fc receptors for IgG are redundant in facilitating presentation of immune complex derived antigen to CD8+ T cells in vivo.@Molecular immunology, 43(13), 2045-2050.@Yes$Chargelegue, D., Drake, P. M., Obregon, P., Prada, A., Fairweather, N., & Ma, J. K. (2005).@Highly immunogenic and protective recombinant vaccine candidate expressed in transgenic plants.@Infection and immunity, 73(9), 5915-5922.@Yes$Marusić-Galesić, S., Marusić, M., & Pokrić, B. (1992).@Cellular immune response to the antigen administered as an immune complex in vivo.@Immunology, 75(2), 325.@Yes$Pepponi, I., Diogo, G. R., Stylianou, E., van Dolleweerd, C. J., Drake, P. M., Paul, M. J., ... & Reljic, R. (2014).@Plant‐derived recombinant immune complexes as self‐adjuvanting TB immunogens for mucosal boosting of BCG.@Plant biotechnology journal, 12(7), 840-850.@Yes$Grifoni, A., Sidney, J., Zhang, Y., Scheuermann, R. H., Peters, B., & Sette, A. (2020).@A sequence homology and bioinformatic approach can predict candidate targets for immune responses to SARS-CoV-2.@Cell host & microbe, 27(4), 671-680.@Yes$Zheng, M., & Song, L. (2020).@Novel antibody epitopes dominate the antigenicity of spike glycoprotein in SARS-CoV-2 compared to SARS-CoV.@Cellular & molecular immunology, 17(5), 536-538.@Yes$Du, L., He, Y., Zhou, Y., Liu, S., Zheng, B. J., & Jiang, S. (2009).@The spike protein of SARS-CoV-a target for vaccine and therapeutic development.@Nature Reviews Microbiology, 7(3), 226-236.@Yes$Daniell, H., Lee, S. B., Panchal, T., & Wiebe, P. O. (2001).@Expression of the native cholera toxin B subunit gene and assembly as functional oligomers in transgenic tobacco chloroplasts.@Journal of molecular biology, 311(5), 1001-1009.@Yes$Tregoning, J. S., Nixon, P., Kuroda, H., Svab, Z., Clare, S., Bowe, F., ... & Maliga, P. (2003).@Expression of tetanus toxin fragment C in tobacco chloroplasts.@Nucleic acids research, 31(4), 1174-1179.@Yes$Koya, V., Moayeri, M., Leppla, S. H., & Daniell, H. (2005).@Plant-based vaccine: mice immunized with chloroplast-derived anthrax protective antigen survive anthrax lethal toxin challenge.@Infection and immunity, 73(12), 8266-8274.@Yes$Chebolu, S., & Daniell, H. (2007).@Stable expression of Gal/GalNAc lectin of Entamoeba histolytica in transgenic chloroplasts and immunogenicity in mice towards vaccine development for amoebiasis.@Plant biotechnology journal, 5(2), 230-239.@Yes$Birch‐Machin, I., Newell, C. A., Hibberd, J. M., & Gray, J. C. (2004).@Accumulation of rotavirus VP6 protein in chloroplasts of transplastomic tobacco is limited by protein stability.@Plant Biotechnology Journal, 2(3), 261-270.@Yes$Glenz, K., Bouchon, B., Stehle, T., Wallich, R., Simon, M. M., & Warzecha, H. (2006).@Production of a recombinant bacterial lipoprotein in higher plant chloroplasts.@Nature biotechnology, 24(1), 76-77.@Yes$Tacket, C. O., Mason, H. S., Losonsky, G., Clements, J. D., Levine, M. M., & Arntzen, C. J. (1998). Immunogenicity in humans of a recombinant bacterial antigen delivered in a transgenic potato. Nature medicine, 4(5), 607-609.@undefined@undefined@Yes$Tacket, C. O., Pasetti, M. F., Edelman, R., Howard, J. A., & Streatfield, S. (2004).@Immunogenicity of recombinant LT-B delivered orally to humans in transgenic corn.@Vaccine, 22(31-32), 4385-4389.@Yes$Tacket, C. O., Mason, H. S., Losonsky, G., Estes, M. K., Levine, M. M., & Arntzen, C. J. (2000).@Human immune responses to a novel Norwalk virus vaccine delivered in transgenic potatoes.@The journal of infectious diseases, 182(1), 302-305.@Yes$Kapusta, J., Modelska, A., Figlerowicz, M., Pniewski, T., Letellier, M., Lisowa, O., ... & Legocki, A. B. (1999).@A plant‐derived edible vaccine against hepatitis B virus.@The FASEB journal, 13(13), 1796-1799.@Yes$Thanavala, Y., Mahoney, M., Pal, S., Scott, A., Richter, L., Natarajan, N., ... & Mason, H. S. (2005).@Immunogenicity in humans of an edible vaccine for hepatitis B.@Proceedings of the National Academy of Sciences, 102(9), 3378-3382.@Yes$Yusibov, V., Hooper, D. C., Spitsin, S. V., Fleysh, N., Kean, R. B., Mikheeva, T., ... & Koprowski, H. (2002).@Expression in plants and immunogenicity of plant virus-based experimental rabies vaccine.@Vaccine, 20(25-26), 3155-3164.@Yes$Shoji, Y., Farrance, C. E., Bautista, J., Bi, H., Musiychuk, K., Horsey, A., ... & Yusibov, V. (2012).@A plant‐based system for rapid production of influenza vaccine antigens.@Influenza and other respiratory viruses, 6(3), 204-210.@Yes$Buyel, J. F., Twyman, R. M., & Fischer, R. (2017).@Very-large-scale production of antibodies in plants: The biologization of manufacturing.@Biotechnology Advances, 35(4), 458-465.@Yes$D’Aoust, M. A., Lavoie, P. O., Couture, M. M. J., Trépanier, S., Guay, J. M., Dargis, M., ... & Vézina, L. P. (2008).@Influenza virus‐like particles produced by transient expression in Nicotiana benthamiana induce a protective immune response against a lethal viral challenge in mice.@Plant biotechnology journal, 6(9), 930-940.@Yes$D’Aoust, M. A., Couture, M. M. J., Charland, N., Trépanier, S., Landry, N., Ors, F., & Vézina, L. P. (2010).@The production of hemagglutinin‐based virus‐like particles in plants: a rapid, efficient and safe response to pandemic influenza.@Plant biotechnology journal, 8(5), 607-619.@Yes$Nochi, T., Yuki, Y., Katakai, Y., Shibata, H., Tokuhara, D., Mejima, M., ... & Kiyono, H. (2009).@A rice-based oral cholera vaccine induces macaque-specific systemic neutralizing antibodies but does not influence pre-existing intestinal immunity.@The Journal of Immunology, 183(10), 6538-6544.@Yes$Koya, V., Moayeri, M., Leppla, S. H., & Daniell, H. (2005).@Plant-based vaccine: mice immunized with chloroplast-derived anthrax protective antigen survive anthrax lethal toxin challenge.@Infection and immunity, 73(12), 8266-8274.@Yes$Krenek, P., Samajova, O., Luptovciak, I., Doskocilova, A., Komis, G., & Samaj, J. (2015).@Transient plant transformation mediated by Agrobacterium tumefaciens: Principles, methods and applications.@Biotechnology Advances, 33(6), 1024-1042.@Yes$Gretler, C. (2022).@Tobacco-Based Coronavirus Vaccine Poised for Human Tests Bloomberg.@May 15.@Yes$Palca, J. (2020).@Tobacco plants contribute key ingredient for COVID-19 Vaccine.@@Yes$Mullan, K. (2020).@Tobacco Giant BAT Says It Could be Making 1 to 3 Million COVID-19 Vaccines a Week by June.@@Yes$Chung, Y. H., Cai, H., & Steinmetz, N. F. (2020).@Viral nanoparticles for drug delivery, imaging, immunotherapy, and theranostic applications.@Advanced Drug Delivery Reviews, 156, 214-235.@Yes$Mahmood, N., Nasir, S. B., & Hefferon, K. (2020).@Plant-based drugs and vaccines for COVID-19.@Vaccines, 9(1), 15.@Yes$Kumar, A. U., Kadiresen, K., Gan, W. C., & Ling, A. P. K. (2021).@Current updates and research on plant-based vaccines for coronavirus disease 2019.@Clinical and Experimental Vaccine Research, 10(1), 13.@Yes$Commandeur, U., Twyman, R. M., & Fischer, R. (2003).@The biosafety of molecular farming in plants.@CABI Reviews, (2003), 9-pp.@Yes$Wagner, B., Fuchs, H., Adhami, F., Ma, Y., Scheiner, O., & Breiteneder, H. (2004).@Plant virus expression systems for transient production of recombinant allergens in Nicotiana benthamiana.@Methods, 32(3), 227-234.@Yes
<#LINE#>Threats of poor indoor air quality and sick building syndrome in academic institutions: A systematic review<#LINE#>Nur Batrisyia @Azlan,Dayana Hazwani Mohd Suadi @Nata <#LINE#>33-39<#LINE#>4.ISCA-RJRS-2021-033.pdf<#LINE#>Department of Diagnostic and Allied Health Science, Faculty of Health and Life Sciences, Management and Science University, 40100 Shah Alam, Selangor, Malaysia@Center for Toxicology and Health Risk Studies, Faculty of Health Sciences, UniversitiKebangsaan Malaysia, Jalan Raja Muda Abdul Aziz, 50300 Kuala Lumpur, Malaysia<#LINE#>16/12/2021<#LINE#>14/12/2022<#LINE#>Students spend an average of more than five hours a day in school, so it is critical that they have access to healthy and productive indoor environments. This paper, therefore, focuses on the importance of IAQ studies in ensuring the health of educational institutions. Particulate matter, carbon dioxide, and other hazardous elements in the air were evaluated for their impact on the health and well-being of students. Sick building syndrome (SBS) is also examined in this paper, as is poor indoor air quality (IAQ). Techniques and strategies for assessing indoor air quality (IAQ) vary widely in their importance and frequency of use, according to various studies. SBS symptoms have been linked to poor indoor air quality (IAQ) in classrooms due to high levels of carbon dioxide, furnishings, and occupants, according to numerous studies. To gain a better understanding of how indoor air quality affects everything from student health and performance to productivity and cognitive function, more research and studies are needed. These studies and research will lead to better IAQ measurements and assessment and sampling techniques.<#LINE#>Dias Pereira, L., Raimondo, D., Corgnati, S. P., & Gameiro da Silva, M. (2014).@Assessment of indoor air quality and thermal comfort in Portuguese secondary classrooms: Methodology and results.@Building and Environment, 81, 69–80. https://doi.org/10.1016/j.buildenv.2014.06.008@Yes$Khalafalla, M. M., Banjar, F. M., Elamin, F. O., Babalghith, A. O., Omar, A., Bahathiq, A. A. A. M., ... & Badran, R. A. (2018).@Indoor Air Quality and Prevalence of Sick Building Syndrome Among Office Workers in Umm Al-Qura University in Kingdom of Saudi Arabia.@Australian Journal of Basic and Applied Sciences, 12(12), 26-31.@Yes$Tsantaki, E., Smyrnakis, E., Constantinidis, T. C., & Benos, A. (2022).@Indoor air quality and sick building syndrome in a university setting: A case study in Greece.@International journal of environmental health research, 32(3), 595-615.@Yes$Amin, N. D. M., Akasah, Z. A. & Razzaly, W. (2015).@Architectural Evaluation of Thermal Comfort: Sick Building Syndrome Symptoms in Engineering Education Laboratories.@Procedia - Social and Behavioral Sciences, 204, 19–28. https://doi.org/10.1016/j.sbspro.2015.08.105@Yes$Kamaruddin, A. S., Jalaludin, J., & Choo, C. P. (2015).@Indoor air quality and its association with respiratory health among malay preschool children in Shah Alam and Hulu Langat, Selangor.@Advances in Environmental Biology, 9(9), 17–26.@Yes$Nor Faeiza, M., Juliana, J., & Chua, P. H. (2016).@Retrofitting and Purposed-built Buildings: Indoor air quality and Sick Building Syndrome among private higher learning institution students in Kuala Lumpur and Selangor.@Malaysian Journal of Public Health Medicine, 16(January), 106–112.@Yes$Wu, Y., Lu, Y., & Chou, D. C. (2018).@Indoor air quality investigation of a university library based on field measurement and questionnaire survey.@International Journal of Low-Carbon Technologies, 13(2), 148–160.@Yes$Zainal, Z. A., Hashim, Z., Jalaludin, J., Lee, L. F., & Hashim, J. H. (2019).@Sick Building Syndrome among Office Workers in relation to Office Environment and Indoor Air Pollutant at an Academic Institution, Malaysia.@Malaysian Journal of Medicine and Health Sciences, 15(3), 126–134.@Yes$Yee, T. C. (2014).@Indoor Environmental Quality (IEQ): A Case Study in Taylor’s Universiti, Malaysia.@International Journal of Engineering and Applied Sciences, 5(07), 1–11.@Yes$Argunhan, Z. & Avci, A. S. (2018).@Statistical Evaluation of Indoor Air Quality Parameters in Classrooms of a University.@Advances in Meteorology, 1–10.@Yes$Cionita, T., Adam, N. M., Jalaludin, J., Mansor, M., & Siregar, J. P. (2014).@Measurement of indoor air quality parameters in daycare centres in Kuala Lumpur Malaysia.@Applied Mechanics and Materials, 564(June), 245–249. https://doi.org/10.4028/www.scientific.net/AMM.564.245@Yes$Er, C. M., Sunar, N. M., Leman, A. M., Othman, N., Emparan, Q., Parjo, U. K., … Ideris, N. A. (2015).@The Evaluation of Indoor Microbial Air Quality in Two New Commissioning Higher Educational Buildings in Johor, Malaysia.@Applied Mechanics and Materials, 773–774, 1068–1072.@Yes$Sulaiman, S. A., Isa, N., Raskan, N. I., & Harun, N. F. C. (2013).@Study of indoor air quality in academic buildings of a university.@Applied Mechanics and Materials, 315, 389–393.@Yes
<#LINE#>Psychoactive Substances: Overview of their identification techniques<#LINE#>Richa @Srivastava <#LINE#>40-51<#LINE#>5.ISCA-RJRS-2023-001.pdf<#LINE#>Department of Applied Chemistry, Delhi Technological University, Delhi – 110042, India<#LINE#>11/1/2023<#LINE#>19/3/2023<#LINE#>The rapidly increasing trend of the use of psychoactive substances among youth is alarming. The lack of awareness about their harmful health effects leads to their misuse. Hence, their manufacture, possession, and use are kept under control by the Government. Fast identification and quantification of these substances are of paramount importance. The methods like HPTLC and HPLC have been extensively used for their analysis and quantification. This review article covers the basics of psychoactive substances, their addictions, regulations, analysis, and identification with the help of HPTLC and HPLC.<#LINE#>Matson, J.L. and Neal D. 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Ongoing technological innovations are enabling the use of modernized techniques to create nanoparticles. The review provides an extensive exploration of these techniques, their biological and chemical properties, and therapeutic impact. The research examines the role of silver nanoparticles, which are commonly used in food packaging and preservation due to their antibacterial and anti-browning properties, and the potential applications of other metallic particles for similar purposes. Furthermore, silver nanoparticles' digestion and physiological benefits, such as their action on mucosa-associated lymphatic tissuesare addressed in detail. These nanoparticles are recommended for medicinal use due to their potential health benefits. Researchers have focused on metallic nanoparticles, particularly magnetic nanoparticles, for their ability to prevent microbial growth. 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