International Science Community Association Research Journal of Recent Sciences 2277 - 2502 1 12 2012 December 2 Tannins: An Antinutrient with Positive Effect to Manage Diabetes 70 73 EN Mohamadian Zahra 1 Department of Computer engineering, Shahrood Branch, Islamic Azad University, Shahrood, IRAN M. Bharani 1 Department of Textile - Fashion Technology, Bannari Amman Institute of Technology, Sathyamangalam, Erode District, TN, INDIA Gowda R.V.Mahendra 2 VSB College of Engineering, Karur, Tamil Nadu, INDIA AdaneAlemmebrat Kiflu 1 Department of Physical Education-Andhra University (AU), Visakhapatnam, INDIA Reddy R.C. 2 SyamBabu M. 3 Mohammed M.B. 1 Department of Applied Science, College of Science and Technology, Kaduna Polytechnic, Kaduna, NIGERIA Mohammed S.S. 2 Adewumi A.A.J. 3 Farshidfar Ramin 1 Sama Technical and Vocational Training College, Islamic Azad University, Qaemshahr Branch, Qaemshahr, IRAN Abbasali Ranjbar 2 Department of Architecture, Sari Branch, Islamic Azad University, Sari, IRAN Srinivas Mondam. 1 Lecturer, Department of Physiotherapy, Windfield International College, Kuala Lumpur, MALAYSIA SrikanthBabu V. 2 Lecturer, Department of Anatomy, MSU, Kuala Lumpur, MALAYSIA KumarB. Raviendra 3 Jalaja Prakash 4 N. Mayavan 1 Department of Futures Studies Madurai Kamaraj University, Madurai, INDIA Sundaram A. 2 VelusamySaranya Akilanpuram 1 Department of Chemistry, Karpagam University, Coimbatore-21, Tamil Nadu, INDIA Subban Ravi 2 Ismail K. 1 Faculty of Management and Human Resource Development, University Technology, MALAYSIA Hussain J. 2 Shah F.A. 3 Hussain A. 4 Ranjbar Abbas 1 Orientology, State University of Yerevan, ARMENIA Tank NileshR 1 School of Mechanical and Building Sciences, VIT University, Vellore-632014, TN, INDIA ThundilKaruppa Raj 2 D. Padmavathi 1 Department of Food and Nutrition, Mother Teresa Women’s University, Kodaikanal, INDIA PrabhavathyDevi N. 2 Department of Home Science, Queen Mary’s College, Chennai, INDIA SheikhKashif Raffat 1 Department of Computer Science and I.T, Federal Urdu University of Arts, Sciences and Technology, Karachi, PAKISTAN MuhammadShahab Siddiqui 2 HIIT, FEST, Hamdard University, Karachi, PAKISTAN Siddiq Muhammad 3 Farhan Shafiq 4 Kumari M. 1 Deptt of Foods and Nutrition, College of Home Science, MPUAT, Udaipur, Rajasthan, INDIA Jain S. 2 > Review Paper 2012 3 7 2012 December 2 Plant tannins, including hydrolysable and condensed varieties, are well known antioxidants in medicinal plants, foods, and edible fruits. Phenolic compounds and flavonoids are a unique category of plant phytochemicals especially in terms of their vast potential health-benefiting properties. Tannins are potential antioxidants. They have been considered to be cardio-protective, anti-inflammatory, anti-carcinogenic and anti-mutagenic, among others. Tannins enhance glucose uptake and inhibit adipogenesis, thus being potential drugs for the treatment of NIDDM.Tannins can improve the pathological oxidativestate of a diabetic situation. Many earlier studies suggested that phenolic compounds and flavonoids protect against many types of cancer. In particular, phenolic compounds have been reported to modulate intracellular signalling through PI3K and p38 MAPK pathways, modulating the activity of target enzymes and modulating gene expression. Condensed Tannins have a wide range of biological and pharmacological activities including antioxidative, cardio-protective, antitumor, antibacterial, antiviral, anti-inflammatory and immune-modulatory. These specific phytochemicals provide a promising area of research for future human studies and potential nutraceutical for disease prevention and treatment. Copyright@ International Science Community Association