International Science Community Association Research Journal of Chemical Sciences 2231-606X 7 12 2017 12 18 A comprehensive review on secondary metabolites of Nigella sativa L (Seeds) 16 29 EN Suganya V. 1 PG and Research Department of Biochemistry, Mohamed Sathak College of Arts & Science, Sholinganallur, Chennai, Tamilnadu, India Anuradha V. 2 PG and Research Department of Biochemistry, Mohamed Sathak College of Arts & Science, Sholinganallur, Chennai, Tamilnadu, India Ali M. Syed 3 PG and Research Department of Biochemistry, Mohamed Sathak College of Arts & Science, Sholinganallur, Chennai, Tamilnadu, India Sangeetha P. 4 PG and Research Department of Biochemistry, Mohamed Sathak College of Arts & Science, Sholinganallur, Chennai, Tamilnadu, India Bhuvana P. 5 PG and Research Department of Biochemistry, Mohamed Sathak College of Arts & Science, Sholinganallur, Chennai, Tamilnadu, India Usman Shumaila 1 Food and Biotechnology Research Centre, PCSIR Laboratories Complex, Ferozpur Road Lahore, Pakistan Yasmeen Ammara 2 Food and Biotechnology Research Centre, PCSIR Laboratories Complex, Ferozpur Road Lahore, Pakistan Nazir Saima 3 Food and Biotechnology Research Centre, PCSIR Laboratories Complex, Ferozpur Road Lahore, Pakistan Khan Shaista J. 4 Food and Biotechnology Research Centre, PCSIR Laboratories Complex, Ferozpur Road Lahore, Pakistan Ali Sakhawat 5 Food and Biotechnology Research Centre, PCSIR Laboratories Complex, Ferozpur Road Lahore, Pakistan Kalim Imran 6 Food and Biotechnology Research Centre, PCSIR Laboratories Complex, Ferozpur Road Lahore, Pakistan Meenal Gupta 1 School of Studies in Chemistry and Biochemistry, Vikram University, Ujjain 456010, MP, India B.K. Mehta 2 School of Studies in Chemistry and Biochemistry, Vikram University, Ujjain 456010, MP, India > Review Paper 2017 8 13 2017 12 18 Nigella sativa L. synthesizes and accumulates a variety of biological active secondary metabolites. Due to various substances isolated and identified the claim made in traditional medicinal system. Seeds are generally called kalongi (Ranunculacae) is an annual flowering plant, originate from S. W. Asia. Seeds and NSO showed as a folk medicine for a prehistoric usage in all systems of medicines and are used as food also. This comprehensive account provides a botanical distribution of plant, chemical constituents and pharmacological potential are reviewed and summarized the information focusing on its wide spectrum biological and medicinal properties including anti-tumor, antipyretic, analgesic, antinematode, antihypertensive, antidiabetic, antiulcerogenic and anti- bacterial as well as dietary nutritive supplements and also focused on synthesis and properties of nanopaticles due to secondary metabolites show reducing and stabilizing activity. Copyright@ International Science Community Association