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Synthesis, Characterization of 3, 4, 5 - Isoxazolines and Antimicrobial Screening

Author Affiliations

  • 1Department of Chemistry, Vidnyan Mahavidyalaya Malkapur, Dist. Buldhana 443101, Maharashtra, India

Res.J.chem.sci., Volume 6, Issue (7), Pages 16-19, July,18 (2016)


A series of 3, 4, 5 substituted isoxazolines were synthesized via flavanone. Flavanones reacting with hydroxyl amine hydrochloride to form substituted of 3, 4, 5 isoxazolines. All these compounds are characterized by resources of their UV, IR, 1H NMR spectroscopic information. Synthesized compounds evaluate for their antimicrobial bustle. All the compounds exhibited weak to reasonable bustle against all organisms except three which shows strong bustle.


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