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Kinetics of Oxidation of Vitamin-B3 (Niacin) by Sodium N-bromo benzenesulphonamide (Bromamine-B) in HCl Medium and Catalysis by Ru(III) ion

Author Affiliations

  • 1Department of Chemistry, Yuvaraj’s college, University of Mysore, Mysore -570005, INDIA
  • 2Department of studies in Chemistry, Manasagangothri, University of Mysore, Mysore, INDIA

Res.J.chem.sci., Volume 2, Issue (8), Pages 26-30, August,18 (2012)


Kinetics of uncatalyzed and Ru(III) catalyzed oxidation of vitamin-B3 (niacin) by the titled compound (bromamine-B) in HCl medium has been studied at 303K. The uncatalyzed reaction shows a first order dependence of the rate on (BAB) and (vitamin-B3), inverse fractional order in (acid). The Ru(III) Catalyzed reaction on the other hand shows a first order behavior on each of (BAB) and (vitaminB3), fractional order dependence on Ru(III) and inverse fractional order in (acid). The reaction rate shows inverse fractional order (benzenesulphonamide) in both uncatalyzed and Ru(III) ion catalyzed reactions. Addition of halide ions, variation of ionic strength and dielectric constant of the medium had no effect on the reaction rate. Activation parameters have been evaluated from the arrhenius plots, mechanisms consistent with the above kinetic data have been proposed.


  1. Mahadevappa D.S., Ananda S., Murthy A.S.A. and Rangappa K.S., Tetrahedron, 10, 1673 (1984)
  2. Rao P.V.S., Subbaiah K.V. and Murthy P.S.N., React Kinet, Catol, Lett., 10, 79, (1979)11, 287 (1979)
  3. Venkatesha B.M., Ananda S. and Mahadevappa D.S., Indian J. Chem., 30A, 789-792 (1991)
  4. Ananda S., Venkatesha B.M., Mahadevappa D.S. and Madegowda N.M., Int J. Chem Kinet., 25, 755-770 (1993)
  5. Capella-Peiro E., Monferrer-ponsL., Garca-Alvarez-Coque C. and Esteve-Romeroj, Analytical chimica Acta, 427, 193-100 (2001)
  6. Khan Seemab, Rai M.K., Gupta U.K. and Rai J.K., Indian Journal of chemistry, 44A, 98-101 (2005)
  7. Wei Wang, Alice Basinger, Richard A. Neese, Barryshane, Su-A Myong, Mark Christiansen and Marc K Hellerstein., Am.J. Physiol Endocrinal, metab, 280(3) E 540-547 (2001)
  8. Ronald B. Goldberg and Terry A. Jacobson, Mayoclin Proc., 83(4), 470- 478 (2008)
  9. Wei Wang, Alice Basinger, Richard A Neese, Mark Christiansen and Marc K., Heller stein, Am.J. P. Physiol. Endocrinal. Metab, 279(1), E 50 (2000)
  10. Dayalan A. and R. Vijayaraghvan V., Indian J. Chem, 40A, 959 (2001)
  11. Bundareva V.M., Ovchinnikava E.V. and rushkevich T.V., React Kinet and Cat Lett, 94(2), 327-335 (2008)
  12. Sonawane Vilas Y., Res.J. Chem. Sci., 1(1), 25-30 (2011)
  13. Medjor O.W., Egharevba F., Akpoveta O.V., Ize-Iyamu O.K. and Jatto E.O., Res. J. Chem. Sci., 2(1), 38-44 (2012)
  14. Atohoun Y.G.S., Kuevi U.A., Kpota A.H. and Mensah J.B., Res.J. Chem. Sci., 1(8), 18-23 (2011)
  15. Ahmed M.S. and Mahadevappa D.S., Talanta, 27, 669 (1980)
  16. Furniss B.S., Hannatord A.J., Smith P.W.G. and Tatchell A.R., Vogels Text book of organic chemistry, Pearson Publication, 1213 (2009)
  17. Pryde B.G. and Soper F.G., J. Chem., Soc, 1582 (1926)514 (1931)
  18. Morris J.C., Salazar J.A. and Wineman M.A., J. Ame, Chem soc., 70, 2036 (1948)
  19. Bishop E. and Jennings V.J., Talanta, 1, 197 (1958)
  20. Narayanan S.S., and Rao V.R.S., Radiochem, Acta, 32, 211 (1983)
  21. Subhashini M., Subramanian M. and Rao V.R.S., Talanta, 32, 1082 (1985)
  22. Cady H.H. and Connick R.E., J Am chem. Soc, 80, 2646 (1958)
  23. Connick R.E. and Fine D.A., J Am chem. Soc, 82, 4187 (1960)
  24. Davtokratova T., Analytical chemistry of ruthenium, Academy of Sciences, USSR, 54,71, 97 (1963)
  25. Griffith W.P., The chemistry of the rare platinum metals, (Interscience publishers), 141 (1967)
  26. Backhours J.R., Doyer F.D. and Shales N., Proc. Rov soc, 83, 146 (1950)
  27. Singh B. Singh N.B. and Saxena B.B.L., J. Indian Chemical Soc., 61, 319 (1984)
  28. Singh B., Singh P.K. and Singh D., J. mol. Cat, 78, 207 (1988)
  29. Ananda S., Venkatesha B.M., Mahadevappa D.S. and Madegowda N.M., Int J. Chem Kinet 25, 755 (1993)