International Science Community Association Research Journal of Chemical Sciences 16 3 2026 10 18 A Review on Synthesis of some New Heterocyclic Compounds and Study of their Microbial Activities 42 46 EN Mohammed Jibrin 1 Department of Chemistry, Faculty of Natural & Applied Sciences, Nasarawa State University, Keffi, Nigeria Aremu Matthew Olaleke 2 Department of Chemistry, Faculty of Physical Sciences, Federal University of Lafia, Nigeria Usman Abdullahi 3 Department of Chemistry, Faculty of Physical Sciences, Federal University of Lafia, Nigeria Pare Brijesh 1 Department of Photochemistry, Govt. Madhav Science P.G. College, Ujjain, M.P., India Geed Poonam 2 Department of Photochemistry, Govt. Madhav Science P.G. College, Ujjain, M.P., India Oluchukwu Ndukaire Victory 1 Chemistry Advanced Research Centre, Sheda Science and Technology Complex, Abuja, Nigeria Favour Okonna Chinonso 2 Biotechnology Advanced Research Centre, Sheda Science and Technology Complex Abuja, Nigeria Chinenye Loveth Ogbodo 3 Biotechnology Advanced Research Centre, Sheda Science and Technology Complex Abuja, Nigeria Ajunwa Ameh David 4 Biotechnology Advanced Research Centre, Sheda Science and Technology Complex Abuja, Nigeria Emmanuel David 5 Biochemistry Department, Ibrahim Badamasi Babangida University, Lapai, Niger State, Nigeria Idris Usman 6 Biochemistry Department, Ibrahim Badamasi Babangida University, Lapai, Niger State, Nigeria Nkemakonam Olime Moses 7 Chemistry Advanced Research Centre, Sheda Science and Technology Complex, Abuja, Nigeria Tiwari Smita 1 Department of Chemistry, Shri Shankaracharya Professional University, Bhilai, 491001, India Diwan Vijita 2 Department of Chemistry, Shri Shankaracharya Professional University, Bhilai, 491001, India Sar Santosh Kumar 3 Department of Applied Chemistry, Bhilai Institute of Technology, Durg, 491001, India P.T. Anjana 1 Research Department of Chemistry, Government College, Madappally, Vadakara, 673102 Kerala, India B Preetha 2 Research Department of Chemistry, Government College, Madappally, Vadakara, 673102 Kerala, India Drakshe S.E. 1 Department of Chemistry, SSMM College Pachora, Dist. Jalgaon, 424201, MS, India Garud R.S. 2 Department of Chemistry, SSMM College Pachora, Dist. Jalgaon, 424201, MS, India > Review Paper 2026 7 30 2026 10 18 Chalcones, a group of compounds having interesting biological activities. Many of aromatic ketones are used as bactericides, disinfectant etc. It has wide range of bioactivity like antimycotic, anti-oxidant, anti-malaria, anti-tubercular, anti-gout, anti-bacterial, anti-ulcer, anti-cancer, insecticidal, anti-protozoal, anti-steroidal etc. Chalcones and their derivatives are used as a man-made sweetener, scintillator, polymerization catalyst, fluorescence brightening agent, organic brightening agent, visible light, ultraviolet light (UV) and aging. They are all reactive to many of the reagents such as hydrazine's, aminophenol's etc. containing the keto-ethylenic group in their structure. The Chalcones are used in clarifying structures of natural products. Copyright@ International Science Community Association