International Science Community Association Research Journal of Chemical Sciences 16 2 2026 06 18 Synthesis, Spectral Sharacterization and Antimicrobial Studies of Ni(II), Co(II) and Mn(II) Complexes with Schiff Base Ligand derived from 3,5-Dibromosalicylaldehyde 21 29 EN Gupta Swaroopa Rani N. 1 Department of Chemistry, Brijlal Biyani Science College, Amravati, Maharashtra India Chaudhari Harshida G. 1 Department of Chemistry, Shree Jayendrapuri Arts and Science College, Bharuch, Gujarat, India Vashi Rajendra T. 2 Chemistry Department, Navyug Science College, Rander Road, Surat, Gujarat, India Sakhare D. T. 1 Department of Chemistry, Shivaji, Art’s, Comm. & Science College Kannad. Dist. Chhatrapti Sambhajinagar-431103, MS, India > Research Paper 2025 12 7 2026 06 18 A novel Schiff base ligand was created by combining 2-amino-4-chloro-6-methylpyrimidine with 3,5-Dibromosalicylaldehyde through a condensation reaction. Metal complexes were formed by reacting the Schiff base with Iron nitrate in an ethanol solution. These complexes were then collected, cleaned, and dried. The Schiff base appears pale yellow, while the complexes with Ni(II), Co(II), and Mn(II) exhibit a light yellow color. Characterization of the synthesized compounds was performed using FT-IR, 1H-NMR, and UV-Vis methods for the ligands, along with FT-IR and UV-Vis for the complexes, as well as assessing all reactions via TLC, molar conductivity, and magnetic susceptibility measurements. The complexes exhibit paramagnetic properties. Molar conductivity assessments showed that all the complexes act as non-electrolytes when dissolved in DMSO. An octahedral structure was determined for all complexes. The ligands function as bidentate (L) through their phenolic (OH) group and azomethine nitrogen. Both the ligand and its complexes were tested for antifungal and antibacterial effects against different strains, including Aspergillus niger, Penicillium chrysogenum, Fusarium moneliforme, Aspergillus flavus, and Escherichia coli, Salmonella typhi, Staphylococcus aureus,B. subtilis. The findings reveal that the complexes demonstrated significant antifungal and antibacterial activity. Copyright@ International Science Community Association