<p><span style=\"line-height: 150%; font-family: \'Times New Roman\',\'serif\'; font-size: 12pt; mso-bidi-font-size: 14.0pt;\">A number of benzothiazole-2-ylsulfanyl derivatives 2-(1,3-Benzothiazol-2-ylsulfanyl)alkanoylhydrazide and 5-[1-(1,3-Benzothiazol-2-ylsulfanyl)alkyl]-1,3,4-thiadiazole-2-(3H) thione have been synthesised from (1,3-Benzothiazol-2-ylsulfanyl)acetic acid. These compounds were characterized from their F.T.I.R, Mass and <sup>1</sup>H NMR spectral studies. The compound (IIA to IIG) were screened for antibacterial activity and antifungal properties. The compound showed appreciable antifungal but negligible antibacterial activity.</span></p>