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A Controlled Study on Predictors of Type 2 Diabetes in Nodular Diabetic Glomerulosclerosis

Author Affiliations

  • 1 Dept. of General medicine, Princess Esra Hospital, Deccan College Of Medical Sciences, Hyderabad, AP, INDIA
  • 2 Clinical pharmacist, Dept. of General Medicine, Princess Esra Hospital, Hyderabad, INDIA

Int. Res. J. Medical Sci., Volume 2, Issue (9), Pages 9-15, September,28 (2014)


Nodular Diabetic Glomerulosclerosis is one of the most familiar diabetic micro vascular complication. A considerable number type 2 diabetic patients are diagnosed regardless of microalbuminuria and with unconcealed and observable nephropathy upon preliminary examination. About 32 to 42% patients with microalbuminuria in type 2 diabetes develops of noticeable nephropathy with in 4 to 5 years, under standard therapy. It is a case control study. Conducted From January to July 2014.Patients visiting the in-patient department of general medicine are selected who has a history of type 2 diabetes mellitus for more than 5-10 years. The diagnosis of diabetic nephropathy was confirmed by 24 hours urine for albumin excretion rate. The study conducted with an aim to estimate the prevalence of 24 hours urinary albumin excretion and to evaluate the etiologic evidence of urinary albumin, creatinine clearance, Serum creatinine, Blood urea. The results show that The mean 24hour urine albumin level in diabetic nephropathy patients was about 539.65 406.37 and 70.334.52 of the control group. In our study it was found that the combineMean creatinine clearance of males and females in Diabetic nephropathy patients was about 20.524.20 and 94.958.67 of the control group. serum creatinine clearance also helps in providing the information about how well the kidneys are working. the study concludes thatThe role of albumin excretion is very important to detect diabetic nephropathy which is the leading cause of renal disease. And serum creatinine clearance also helps in providing information about the progression of ESRD.


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