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Restricted versus Prolonged Antibiotic Usage in Gynaecological Practice

Author Affiliations

  • 1 Department of Obstetrics and Gynaecology, Hamdard Institute of Medical Sciences and Research, Jamia Hamdard, New Delhi, INDIA

Int. Res. J. Medical Sci., Volume 2, Issue (8), Pages 1-4, August,28 (2014)


Surgical site infection is one of the most common surgical complications. In the best of circumstances, the incidence is around 5%. It has given rise to irrational use of antibiotics, especially in the context of developing countries. It is this misuse of antibiotics that has paved the way for antibiotic resistance becoming a major global public health problem. To compare antibiotic use, cost and consumption before and after initiation of an antibiotic restriction policy in our hospital. The primary outcome was incidence of infectious complications in women undergoing elective/emergency gynaecological and obstetric procedures. The study was a retrospective analysis, conducted over a period of eight months. In-patient data of antibiotic usage and incidence of infectious complications was collected. The results were compared before and after antibiotic restriction policy was practised. There was no change in infectious morbidity in major obstetrical surgeries, minor gynaecological surgeries and vaginal deliveries. There was decrease in infectious morbidity with respect to major gynaecological surgeries. There was a decrease in the antibiotic consumption, no change in the hospital stay and a decrease in cost of treatment. Indiscriminate use of prophylactic antibiotics is associated with selection of antibiotic resistant bacteria. It may also result in de-stabilisation of the patientís ecosystem and actually hamper the healing process.


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