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Materials Saving and Waste Minimization in Indian Pharmaceutical Industries

Author Affiliations

  • 1Department of Civil Engineering, Jadavpur University, Kolkata, INDIA
  • 2 Dept. of Microbiology, Herbicure Healthcare Bio-Herbal Research Foundation, Metro Garden City, Pailan, D.H. Road, Kolkata, INDIA

Res. J. of Pharmaceutical Sci., Volume 2, Issue (2), Pages 20-25, February,30 (2013)


This paper presents different techniques suggested for cleaner production in three pharmaceutical plants. The main focus of this paper is towards evaluation of source reduction and waste minimization. This paper also finds the various other possibilities to reuse the waste produced in the above-mentioned unit. All input materials, starting from raw materials, potable water, purified water, and water for injection and polyethylene granules are so quantified as to fix limit for all raw materials as 2.5 EU/ gm determined through Bacterial Endotoxin Test (BET). An extensive literature review presents different approaches made by leading pharmaceutical industries to save materials and to minimize wastes generated. Attempts to replace organic solvents by aqueous media have been proved to be successful in all respects.It is successfully experimented that in large volume parenterals industry a measure of endotoxin test at raw material stage, intermediate stage and finished stage could save a huge loss of product rejection resulting in saving of materials and waste minimization.Existing formulation of raw materials should be audited time to time to find the scope for reduction of excipients for resource reduction and waste minimization..


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