International Science Community Association International Research Journal of Environmental Sciences 2319 - 1414 1 5 2012 December 22 Relative Study on Blood BTEX, Testosterone Hormone, Kidney and Liver Functions in Gasoline Station Workers, Thailand 48 53 EN Joshi P.P. 1 Dept. of Zoology, Amolakchand Mahavidyalaya, Yavatmal, MS, Maharashtra, INDIA Tiwari Alka 1 Department of Chemistry, Govt. V.Y.T. PG. Autonomous College, Durg, CG, INDIA Sharma Neeraj 2 Sangeetha M. 1 Department of Chemistry, GTN Arts College, Dindigul Tamil Nadu, INDIA Rajendran S. 2 Department of Chemistry, APA College for Arts and Culture Palani, INDIA Sathiyabama J. 3 Department of Chemistry, RVS School of engineering and Technology, Dindigul, Tamil Nadu, INDIA Prabhakar P. 4 Reddy L. 1 Department of Geology, Loyola Degree College, Pulivendla, Kadapa District, AP, INDIA Chandra Sekhar 2 Department of Chemistry, Loyola Degree College, Pulivendla, Kadapa District, AP, INDIA Reddy K.V.Ramana 3 P.G. Department of Geology, R.T.M. Nagpur University, Law College Square, Nagpur, Maharastra, INDIA Humane Sumedh K. 4 Himanshu S.K. 1 Department of Civil Engineering, Graphic Era University, Dehradun, Uttarakhand, INDIA Kumar S. 2 Field consultant, Government of Bihar, INDIA Kumar A. 3 Gupta K.K. 4 Pawar Tushar Anant 1 Dept. of EVS, Mahatma Night Degree College of Arts and Comm., Chembur-71-Mumbai- Maharashtra, INDIA Vedavyasa Mathad 1 2 Department of Mechanical Engineering, Global Academy of Technology, Bangalore, INDIA Lingadalli K Sreepathi 2 Department of Mechanical Engineering, JNN College of Engineering, Shimoga, INDIA Tunsaringkarn Tanasorn 1 College of Public Health Sciences, Chulalongkorn University, Bangkok 10330, THAILAND Zapaung Kalaya 2 Rugsiyothin Anusorn 3 > Research Paper 2012 11 07 2012 December 22 Benzene, toluene, ethylbenzene and xylene are volatile organic compounds (VOCs), usually referred to as BTEX. These compounds can affect human health upon its dose and time of exposures. VOCs are usually found in fuels and other solvents which commonly presented in the environment, however, little known about their effects on the endocrine system. This study aimed to evaluate the relationship between blood BTEX and testosterone hormone, and kidney and liver functions of gasoline station workers. The results showed average blood benzene, toluene, ethylbenzene and m-, p-xylene. o-xylene levels were 284.9, 201.3, 178.7, 35.9, 73.3 µg/L respectively. While average testosterone, blood urea nitrogen (BUN), creatinine, serum glutamic pyruvic transaminase (SGOT), serum glutamic pyruvic transaminase (SGPT) and alkaline phosphatase (ALP) levels were 13.4 nmole/L, 11.8 mg%, 1.0 mg%, 26.0 U/L, 30.9 U/L and 71.8 U/L respectively. Blood testosterone level was inversely related to toluene, m-, p-xylene, o-xylene and total BTEX levels (Linear regression analysis, p0.05). In addition, testosterone level had strongly inverse-relationship to kidney function of BUN and creatinine (linear regression analysis, p0.05 and p0.01). In conclusion, this study supported that BTEX exposures were chronically affected the decreasing of testosterone level in reproductive system as well as to kidney function. Copyright@ International Science Community Association