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Detection of Arctigenin in Ipomoea cairica L. leaves: A potential drug for Japanese encephalitis

Author Affiliations

  • 1Department of Botany, D.D.U. Gorakhpur University, Gorakhpur, Uttar Pradesh, India

Int. Res. J. Biological Sci., Volume 6, Issue (8), Pages 47-49, August,10 (2017)


Ipomoea cairica L. is a perennial herb which grows in unstable sites, such as waste-ground and roadsides in urban areas. It has been reported for several medicinal properties. Literature survey revealed the presence of phenylpropanoid compounds in this plant. One of such compound is Arctigenin. Arctigenin, is a Phenylpropanoid dibenzylbutyrolactone lignan with antinflammatory and antioxidant activities. Recent report suggests that arctigenin inhibits neuronal apoptosis and can reduce the severity of Japanese encephalitis. The presence work confirms the presence of arctigenin in cultivated plant of Ipomoea cairica leaves extract. The dried leaves sample was extracted through column chromatography with ethanol. The extracted samples were subjected to thin layer chromatography (TLC) taking Benzene: Ethyle acetate (9:1 ratio) and high performance liquid chromatography (HPLC) in methanol. Identification of the isolated compounds was done with reference standard using TLC and HPLC. The present study confirms the presence of arctigenin in leaves extract of Ipomoea cairia leaves.


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