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Genetic Diseases in Cattle: A Review

Author Affiliations

  • 1Dept. of Animal Genetics and Breeding, Nagpur Veterinary College, Maharashtra Animal and Fishery Sciences University, Nagpur, MS, INDIA
  • 2Dept. of Animal Genetics and Breeding, Nagpur Veterinary College, Maharashtra Animal and Fishery Sciences University, Nagpur, MS, INDIA
  • 3Dept. of Animal Genetics and Breeding, Nagpur Veterinary College, Maharashtra Animal and Fishery Sciences University, Nagpur, MS, INDIA

Res. J. Animal, Veterinary and Fishery Sci., Volume 2, Issue (2), Pages 24-33, February,24 (2014)


Genetic disease is an illness caused by inborn abnormalities in genes or chromosomes, which are quite rare. The genetic diseases in dairy and beef cattle are tissue specific viz; Skeletal, central nervous system, blood, skin, muscle and ophthalmic. Some genetic diseases like Bovine leukocyte adhesion deficiency (BLAD) are breed specific and affecting significantly on economics of dairy farming. The various scientists had reported the frequency as 3.33% and 4.0% in Iranian Holstein-Friesian and Chinese Holstein cattle respectively. However, in India BLAD carrier was estimated as 3.23% in pure and crossbred Holstein-Friesian only. The details of these genetic diseases with special reference to its definition, genetic cause (DNA mutation) and its clinical symptoms are discussed in the review. In the modern era of animal breeding, Veterinary doctors, animal scientists, cattle breeders and livestock stakeholders should have the awareness of genetic diseases and their implications. The DNA testing is currently available for some of the genetic diseases; however it is necessary to develop it for all the genetic diseases so that breeding sires can be effectively screened for undesirable alleles and culled to avoid further propagation in breeding population. The information in the review can aid in investigating, reporting, treating and suggesting strategies for elimination of undesirable genes from breeding population.


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