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Antilipoxygenase and Antihelmintic Activity of Ginger (Zingiber Officinale) Enriched Cane Jaggery

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Author Affiliations

  • 1Department of Sugar Technology, Sir. M. Visvesvaraya Post Graduate Centre, University of Mysore, Mandya, 571 402, Karnataka, INDIA
  • 2Department of Biochemistry, Adichunchanagiri Biotechnology and Cancer Research Institute, Balagangadharanatha Nagara, 571 448, Nagamangala Taluk, Mandya, Karnataka, INDIA

Res. J. Recent Sci., Volume 4, Issue (8), Pages 62-66, August,2 (2015)

Abstract

Zingiber Officinale enriched jaggery (ZOEJ) at 0.05 %, 0.1 % and 0.2 % concentrations from Co 86032, Co419 and Co 62175 sugarcane varieties were evaluated for lipoxygenase inhibitory and antihelmintic activity. In addition total phenol content of the ZOEJ samples were quantified. Total phenol content of ZOEJ indicated significant difference between enriched and control jaggery and showed a dose dependent increase for all the varieties. ZOEJ showed inhibition of lipoxygenase activity with an EC50 of 0.34, 0.33 and 0.31 mg/mL at 0.05 % Z. officinale enrichment for Co 86032, Co419 and Co 62175 sugarcane varieties, respectively. A positive correlation (r = 0.961, 0.900 and 0.970) was observed between total phenolics and antilipoxygenase activity of ZOEJ for Co 86032, Co419 and Co 62175 varieties. However, ZOEJexhibited antihelmintic activity at 0.5g/mL concentration in all sugarcane varieties but indicated no significant difference in both paralysis and death time of helmintis upon spice enrichment. Hence, dietary supplementation of Z. officinale enriched jaggery may contribute better health benefits.

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