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Prevalence of Hepatitis C Virus Seropositivity among blood donors in a Tertiary care hospital

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Author Affiliations

  • 1 Department of Immunohematology and Blood Transfusion, Dayanand Medical College and Hospital, Ludhiana, 141001, Punjab, INDIA

Int. Res. J. Medical Sci., Volume 3, Issue (2), Pages 22-24, February,28 (2015)

Abstract

Hepatitis C Virus (HCV) is a major cause of post transfusion hepatitis. Seropositivity of HCV among blood donors varies from 0.53%-5.1% in different parts of India. The aim of study is to see the prevalence of anti HCV antibodies among healthy blood donors in Punjab. This retrospective analysis included blood donor screening data from January 2009 to December 2013 (5 years). Donor samples were screened for anti-HCV antibodies by ELISA using HCV UTRA HEPNOSTIKA KIT, Biomerieux, France. Analysisofseropositivity in replacement and voluntary blood donors were compared using the Pearson Chi-Square test. Of the total 1, 56,695 blood units screened, 1.45% (n=2286) were found to be reactive for anti HCV antibodies. The seropositivity of HCV varied from 1.13% to 1.74%. Out of the total blood donors’ positive for anti-HCV antibody, 68.8% were replacement and 31.2% were voluntary and statistically significant (p0.05). The screening of blood products is the only way for preventing the transfusion associated cases of hepatitis. The introduction of donor counseling, screening for different pathogens and donors self exclusion and ensuing a 100% voluntary blood donation will be effective in decreasing the hepatitis rate.

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