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Antimicrobial Susceptibility Pattern of E.coli isolated from urinary tract infections at Al-Quwayiyah General Hospital, Al- Quwayiyah, Kingdom of Saudi Arabia

Author Affiliations

  • 1 Department of Medical Laboratory Sciences, College of Applied Medical Science’s, Al-Quwayiyah, Shaqra University, Kingdom of SAUDI ARABIA
  • 2 Al-Quwayiyah General Hospital, Al- Quwayiyah, Kingdom of SAUDI ARABIA

Int. Res. J. Medical Sci., Volume 2, Issue (2), Pages 18-21, February,28 (2014)

Abstract

Urinary tract infection (UTI) is the most common among all hospital acquired infections worldwide. In UTI, most common organism is E.coli. Organism responsible for the hospital acquired infection may have tendency to develop multiple drug resistance. E.coli acquired from the Al-Quwayiyah General Hospital source may differ in their resistant against antibiotics. This was a retrospective study conducted in an Al-Quwayiyah General hospital to know the prevalence and antibiogram of E.coli. Samples received include mid-stream clean catch urine, suprapubic aspirate and from Foley’s catheter. All the plates were inspected for growth and the isolates were identified by observing colony morphology, Gram-stain characteristics and relevant biochemical tests. The isolates were tested for their antimicrobial susceptibility and the results were interpreted by vitek 2 methods, according to the guidelines of Clinical and Laboratory Standards Institute. Out of 96 samples tested, 53 (55.2%) were positive for E.coli. E.coli was highly resistant to Ampicillin (85.1%) followed by Piperacillin (66.03%) and least resistance was seen with Nalidixic acid (5.6%) and Nitrofurantoin (5.6%) followed by and Ciprofloxacin (11.3%). Knowledge of prevalence and antimicrobial susceptibility pattern of E. coli will help in selecting an appropriate antibiotic for empirical therapy. Formulation of hospital infection control committee and strict adherence to the guidelines of the committee will help in preventing the emergence of drug resistance.

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