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Synthesis, Spectral Characterization and Antifungal Activities of Cr(III), Co(II), Ni(II) and Hg(II) Complexes With Nicotinic Acid Hydrazide and Azide as Ligands

Author Affiliations

  • 1St. Joseph’s College Autonomous, Tiruchirappalli, INDIA
  • 2 Department of Chemistry, Govt. Arts College, Ariyalur, INDIA

Res. J. of Pharmaceutical Sci., Volume 2, Issue (2), Pages 1-6, February,30 (2013)


he mixed Ligand complexes of Cr(III), Co(II), Ni(II) and Hg(II) with nicotinic acid hydrazide(NHA) and azide ion are known as ligands. All the prepared complexes were characterized by elemental analysis, EC measurements, IR, NMR spectral analysis and antifungal studies. From the obtained elemental analysis and spectral data to arrived at the formulae of the complexes. The antifungal activities of complexes compared with those of pure Ligand NHA. All the complexes show less activity against the tested fungus such as A.flavus, A.niger, C.albicance, A.oryzae and A.sojae.


  1. Sidhaya R.V., Dhanawade A.E., Manasa. K. and Aishwarya G., Synthesis, antibmicrobial and antimycobacterial activity of nicotinic acid hydrazide derivatives., Current Pharma Research., 1(2), 135-139 (2011)
  2. Rakesh Narang., Sunil Sharma and Balasubramanian Narasimhan., Evaluation of Anti-inflammatory activity of acid Hydrazide derivatives.,journal for drugs and medicines., 4(2), 15-20 (2012)
  3. Ramalakshmi N., Deepa S., Sumanth Srinivas K. and Puratchikody A. and Arunkumar S., Synthesis, antimicrobial and antimycobacterial activity of nicotinic acid., Rasayan. Journal of Chem., 2(2), 393-396 (2009)
  4. Rakesh Narang., Balasubramanian Narasimhan., Sunil Sharma., Dharmarajan Sriram., Perumal Yogeeswari., Erik De Clercq., Christophe Pannecouque. And Jan Balzarini., Synthesis, antimycobacterial, antiviral, antimicrobial activities, and QSAR studies of nicotinic acid benzylidene hydrazide derivatives., Med.Chem.Research, 21, 1557-76 (2012)
  5. Manisha V.S., Alagwadi K.R., Reyee. N. and Bhanushali M.D., Synthesisand antimicrobial activity of some substituted azomethine derivatives. International Journal of Pharma.Research and Development., 2(9), 63-68 (2010)
  6. Vijey Aanandhi M., Mohammed Hashim Mansoori., Shanmugapriya S., Shiny George. and hanmugasundaram P., Synthesis and In- vitro antioxidant activity of substituted Pyridinyl 1, 3, 4 oxadiazole derivatives., Research Journal of Pharmaceutical, Biological and Chemical Sciences., 1(4), 1083-90 (2010)
  7. Montazero Zohori Morteza., Musavi Sayed Ali Reza. and Jooharishiva., Synthesis, characterization and thermal behavior of some new mercury and cadmium halides coordination compounds of recently synthesized Schiff base, Research Journal of Recent sciences., 1(11), 9-15 (2012)
  8. Kazoo Nakamoto., Infra red and Raman Spectra of Inorganic and Coordination compounds, 3rd Edn., John Wiley and Sons, New York, 270-274 (1978)
  9. Mrinalinil.L. and A.K. Maniharsing., mixed ligand Co(III) complexes with 1-amidino-O-methyl urea and aminoacids, Research Journal of Chemical Sciences., 2(1), 45-49 (2012)
  10. Agarwal Ram K., LakshmanSingh. and Deepak Kumar Sharma., synthesis, spectral and biological properties of Cu (II) complexes of thiosemicarbazones of Schiff base derived from 4-aminoantipyrine and aromatic aldehydes,Bioorganic Chemistry and Applications., 1-10 (2006)