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Autonomic Response to Cold Pressor Test in Relation to ABO Blood Groups

Author Affiliations

  • 1Dept of Physiology, Deccan College of Medical Sciences, DMRL X Roads, Kanchanbagh, Hyderabad 500 058, INDIA
  • 2 Deccan College of Medical Sciences, DMRL X Roads, Kanchanbagh, Hyderabad 500 058, INDIA

Int. Res. J. Biological Sci., Volume 2, Issue (10), Pages 30-35, October,10 (2013)


Studies show that subjects with high cardiovascular sensitivity accompanied by delayed recovery time after the stimulus subsides, are at a comparatively greater risk of cardiovascular morbidity, in specific hypertension, in the later life. The cold press or response is an indicator of sympathetic activity after cold stress. The cold pressor test was done on subjects with various blood groups. The study was conducted on medical students in the age group 17-30 years. The data was analyzed for statistical significance. In the seated blood pressure more than half had a high normal blood pressure (63.31%) followed by normal (35.91%) and grade one hypertension. In the cold pressor reaction more than half ( 83.1%) were normo- reactors and the remaining hyper -reactors (16.9%). More than half (65%) and all (100%) the hyper- reactors had atleast one hypertensive parent in males and females respectively. After the test, blood pressure did not return to normal in more than half of both males (63.45%) and females (57.15%). The relation between the blood pressure and blood group was not statistically significant. We deduce that blood groups have no effect on the cold pressor test. In the seated blood pressure most subjects had a high normal blood pressure which were higher in males compared to females. The hyper- reactors were significantly high in males compared to females. And the history of hypertension even in one parent seems to be a significant factor in hyper -reactors in both males and females. Thus hyper- reactors can take preventive care so as to prevent the cardiac morbidity . The children of hypertensive patients can take preventive life style changes to decrease their risk for developing hypertension in future thus cardiac morbidity.


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