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A Review: Formulation approaches for targeted drug delivery of drugs for Rheumatoid Arthritis

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Author Affiliations

  • 1Department of Pharmaceutics, S.V.U.C.S, S.V. University, Tirupati, AP-517501, India
  • 2Department of Pharmaceutics, S.P.W. Polytechnic, Tirupati, AP-517501, India

Int. Res. J. Biological Sci., Volume 11, Issue (3), Pages 20-24, August,10 (2022)

Abstract

The aim of the present review article is focus on current status of Rheumatoid arthritis and to present various novel approaches for development of formulations and the techniques without inherent of side effects of antiarthritic drugs such NSAID. Rheumatoid arthritis is an auto immune disorder which followed by inflammation and disorder in function also causes depression. By using anti-inflammatory drugs and immunosuppressants together it can be treated. These drugs possess high fatal risk as they have not targeted to the receptor site and thus it shows severe adverse effects. Due to low bioavailability of these drugs, the drug candidates are potentially used in too high doses which causes adverse effects. In order to overcome these adverse effects, to increase the bioavailability and also to induce sustain release targeted drug delivery system may considered to be useful. By using the targeted drug delivery system, specificity of drugs increases, which increases bioavailability and the dose of administered drug get reduced.

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